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Bert L. de Groot

Rockefeller University · US
Area of research
Molecular Biology · Materials Chemistry
Research interest
Research interests include Chemistry, Molecular dynamics, Biophysics, Ion, Ion channel, and KcsA potassium channel.
h-index
citations
8,177
works
15
NIH funding
primary concept
email

Recent publications

Prospective Evaluation of Structure-Based Simulations Reveal Their Ability to Predict the Impact of Kinase Mutations on Inhibitor Binding
The Journal of Physical Chemistry B 2025cited by 10position: middledoi
Atomistic Mechanism of Calcium-Mediated Inward Rectification of the MthK Potassium Channel by Solid-State NMR and MD Simulations
Journal of the American Chemical Society 2025cited by 2position: middledoi
Direct Detection of Bound Ammonium Ions in the Selectivity Filter of Ion Channels by Solid-State NMR
Journal of the American Chemical Society 2022cited by 20position: middledoi
Alchemical absolute protein–ligand binding free energies for drug design
Chemical Science 2021cited by 91position: middledoi
Structure, gating and interactions of the voltage-dependent anion channel
European Biophysics Journal 2021cited by 46position: middledoi
Structural plasticity of the selectivity filter in a nonselective ion channel
IUCrJ 2021cited by 20position: middledoi
The SAMPL6 SAMPLing challenge: assessing the reliability and efficiency of binding free energy calculations
Journal of Computer-Aided Molecular Design 2020cited by 137position: middledoi
A β-barrel for oil transport through lipid membranes: Dynamic NMR structures of AlkL
Proceedings of the National Academy of Sciences 2020cited by 69position: middledoi
The conduction pathway of potassium channels is water free under physiological conditions
Science Advances 2019cited by 60position: middledoi
Identification of kinetic order parameters for non-equilibrium dynamics
The Journal of Chemical Physics 2019cited by 36position: middledoi
A single NaK channel conformation is not enough for non-selective ion conduction
Nature Communications 2018cited by 75position: middledoi
Conotoxin κM-RIIIJ, a tool targeting asymmetric heteromeric K <sub>v</sub> 1 channels
Proceedings of the National Academy of Sciences 2018cited by 31position: middledoi
CHARMM36m: an improved force field for folded and intrinsically disordered proteins
Nature Methods 2016cited by 7,448position: middledoi
Molecular driving forces defining lipid positions around aquaporin-0
Proceedings of the National Academy of Sciences 2012cited by 77position: lastdoi
Molecular Dynamics in Principal Component Space
The Journal of Physical Chemistry B 2012cited by 55position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Adam Lange · Humboldt-Universität zu Berlin6 papers (2018–2025) · 6 papers (2018–2025) · 4 papers (2018–2022)Matteo Aldeghi · Massachusetts Institute of Technology3 papers (2020–2025) · 3 papers (2018–2021)Vytautas Gapsys · Twitter (United States)3 papers (2020–2025)Loren B. Andreas · Université Claude Bernard Lyon 13 papers (2020–2022)Carl Öster · Université Claude Bernard Lyon 13 papers (2019–2025)Chaowei Shi · University of North Texas3 papers (2018–2025) · 2 papers (2021–2022)John D. Chodera · Charité - Universitätsmedizin Berlin2 papers (2020–2025)Sascha Lange · Freie Universität Berlin2 papers (2019–2022)David L. Mobley · University of California, Irvine2 papers (2020–2021)Kumar Tekwani Movellan · University of Delaware2 papers (2020–2022)Saeid Abdolvand · Humboldt-Universität zu Berlin1 papers (2021–2021)Helmut Grubmüller · The University of Texas Southwestern Medical Center1 papers (2016–2016)Raktim N. Roy · Scripps Research Institute1 papers (2021–2021) · 1 papers (2025–2025)Michael K. Gilson · University of California San Diego1 papers (2020–2020)Jan Staněk · Université Claude Bernard Lyon 11 papers (2020–2020)