Area of research
Molecular Biology · Radiology, Nuclear Medicine and Imaging
Research interest
Research interests include Biology, Cell biology, Ubiquitin, Cancer research, Chemistry, and Ubiquitin ligase.
BCDX2–CX3 and DX2–CX3 complexes assemble and stabilize RAD51 filaments
Template-driven scaffolding of SCFFBXO42 regulates PP2A degradation
Rational design of potent small-molecule SMARCA2/A4 degraders acting via the recruitment of FBXO22
Enteropathogenic bacteria evade ROCK-driven epithelial cell extrusion
Chemically-induced degradation of the endoplasmic-reticulum stress sensor IRE1 by a VHL-recruiting chimera
Context-Specific Stress Causes Compartmentalized SARM1 Activation and Local Degeneration in Cortical Neurons
Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation
Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation
Targeting the Hippo pathway in cancers via ubiquitination dependent TEAD degradation
Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine release
Argonaute3-SF3B3 complex controls pre-mRNA splicing to restrain type 2 immunity
Selective PROTAC-mediated degradation of SMARCA2 is efficacious in SMARCA4 mutant cancers
Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection
Defining the carrier proteome limit for single-cell proteomics
Dynamic Regulation of Mitochondrial Import by the Ubiquitin System
Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation
Tumor suppressor BAP1 is essential for thymic development and proliferative responses of T lymphocytes
Mass Spectrometric Quantification of Histone Post-translational Modifications by a Hybrid Chemical Labeling Method