Area of research
Nephrology · Molecular Biology
Research interest
Research interests include Renal Diseases and Glomerulopathies, Receptor Mechanisms and Signaling, Protein Kinase Regulation and GTPase Signaling, and Chronic Kidney Disease and Diabetes.
Podocyte specific knockout (KO) of the natriuretic peptide clearance receptor (NPRC) attenuates diabetic kidney disease (DKD).
Podocyte specific knockout of the natriuretic peptide clearance receptor is podocyte protective in focal segmental glomerulosclerosis.
Pharmacologic blockade of the natriuretic peptide clearance receptor promotes weight loss and enhances insulin sensitivity in type 2 diabetes.
Twist1 in podocytes ameliorates podocyte injury and proteinuria by limiting CCL2-dependent macrophage infiltration.
Blockade of the natriuretic peptide clearance receptor attenuates proteinuria in a mouse model of focal segmental glomerulosclerosis.
Mutations in the Gene That Encodes the F-Actin Binding Protein Anillin Cause FSGS
Mechanisms of the proteinuria induced by Rho GTPases
A Novel Role for Type 1 Angiotensin Receptors on T Lymphocytes to Limit Target Organ Damage in Hypertension
Diabetic Kidney Disease in FVB/NJ Akita Mice: Temporal Pattern of Kidney Injury and Urinary Nephrin Excretion