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Alice P. Chen

Massachusetts Institute of Technology · US
Area of research
Oncology · Molecular Biology
Research interest
Research interests include PARP inhibition in cancer therapy, Lung Cancer Treatments and Mutations, Cancer Genomics and Diagnostics, and Cancer therapeutics and mechanisms.
h-index
67
citations
19,002
works
760
NIH funding
primary concept
Medicine
email

Recent publications

SARC031: A Phase II Trial of Selumetinib and Sirolimus for Patients with Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumors (MPNST).
2026cited by 0position: contributordoi
Crizotinib in Patients with Tumors with MET Amplification or Exon 14 Deletion: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocols C1 and C2.
2026cited by 0position: contributordoi
Supplementary Figure S1 from Crizotinib in Patients with Tumors with <i>MET</i> Amplification or Exon 14 Deletion: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocols C1 and C2
2026cited by 0position: contributordoi
Supplementary Table S1 from Crizotinib in Patients with Tumors with <i>MET</i> Amplification or Exon 14 Deletion: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocols C1 and C2
2026cited by 0position: contributordoi
Supplementary Table S4 from Crizotinib in Patients with Tumors with <i>MET</i> Amplification or Exon 14 Deletion: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocols C1 and C2
2026cited by 0position: contributordoi
Supplementary Figure S2 from SARC031: A Phase II Trial of Selumetinib and Sirolimus for Patients with Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumors (MPNST)
2026cited by 0position: contributordoi
Supplementary Figure S2 from Crizotinib in Patients with Tumors with <i>MET</i> Amplification or Exon 14 Deletion: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocols C1 and C2
2026cited by 0position: contributordoi
Supplementary Figure S3 from Crizotinib in Patients with Tumors with <i>MET</i> Amplification or Exon 14 Deletion: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocols C1 and C2
2026cited by 0position: contributordoi
Supplementary Table S3 from Crizotinib in Patients with Tumors with <i>MET</i> Amplification or Exon 14 Deletion: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocols C1 and C2
2026cited by 0position: contributordoi
Supplementary Table S1 from SARC031: A Phase II Trial of Selumetinib and Sirolimus for Patients with Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumors (MPNST)
2026cited by 0position: contributordoi
Supplementary Figure S5 from Crizotinib in Patients with Tumors with <i>MET</i> Amplification or Exon 14 Deletion: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocols C1 and C2
2026cited by 0position: contributordoi
Supplementary Table S2 from SARC031: A Phase II Trial of Selumetinib and Sirolimus for Patients with Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumors (MPNST)
2026cited by 0position: contributordoi
Supplementary Figure S4 from Crizotinib in Patients with Tumors with <i>MET</i> Amplification or Exon 14 Deletion: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocols C1 and C2
2026cited by 0position: contributordoi
Supplementary Figure S6 from Crizotinib in Patients with Tumors with <i>MET</i> Amplification or Exon 14 Deletion: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocols C1 and C2
2026cited by 0position: contributordoi
Supplementary Figure S1 from SARC031: A Phase II Trial of Selumetinib and Sirolimus for Patients with Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumors (MPNST)
2026cited by 0position: contributordoi
Supplementary Table S2 from Crizotinib in Patients with Tumors with <i>MET</i> Amplification or Exon 14 Deletion: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocols C1 and C2
2026cited by 0position: contributordoi
Supplementary Figure S3 from SARC031: A Phase II Trial of Selumetinib and Sirolimus for Patients with Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumors (MPNST)
2026cited by 0position: contributordoi
Supplementary Table S3 from SARC031: A Phase II Trial of Selumetinib and Sirolimus for Patients with Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumors (MPNST)
2026cited by 0position: contributordoi
Data from Crizotinib in Patients with Tumors with <i>MET</i> Amplification or Exon 14 Deletion: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocols C1 and C2
2026cited by 0position: contributordoi
Supplementary Table S5 from Crizotinib in Patients with Tumors with <i>MET</i> Amplification or Exon 14 Deletion: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocols C1 and C2
2026cited by 0position: contributordoi
Data from SARC031: A Phase II Trial of Selumetinib and Sirolimus for Patients with Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumors (MPNST)
2026cited by 0position: contributordoi
Efficacy and safety of selumetinib in adults with neurofibromatosis type 1 and symptomatic, inoperable plexiform neurofibromas (KOMET): a multicentre, international, randomised, placebo-controlled, parallel, double-blind, phase 3 study
The Lancet 2025cited by 31position: firstdoi
Selumetinib in adults with NF1 and inoperable plexiform neurofibroma: a phase 2 trial.
2025cited by 24position: contributordoi
Ipatasertib in Patients with Tumors with AKT Mutations: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol Z1K.
2025cited by 5position: contributordoi
Phase II Study of Palbociclib in Patients with Tumors with CDK4 or CDK6 Amplification: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol Z1C.
2025cited by 4position: contributordoi
Concordance between Tumor Tissue and Plasma DNA Genotyping in the NCI-MATCH Trial (EAY131).
2025cited by 2position: contributordoi
A Phase I Study of Nilotinib in Combination with Paclitaxel in Patients with Advanced Solid Tumors.
2025cited by 2position: contributordoi
Future Directions and Priorities for Cellular Therapy in Sarcoma: A Report from the Strategic Advances in Sarcoma Science Cell Therapy Breakout.
2025cited by 1position: contributordoi
A Concordance Study among 26 NGS Laboratories Participating in the NCI Molecular Analysis for Therapy Choice Clinical Trial.
2025cited by 0position: contributordoi
Supplementary Table S1 from Phase II Study of Palbociclib (PD-0332991) in <i>CCND1</i>, <i>2</i>, or <i>3</i> Amplification: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol Z1B
2025cited by 0position: contributordoi

Grants

No grants ingested yet.

Frequent collaborators

· 115 papers (2019–2025)Larry Rubinstein · National Institutes of Health71 papers (2018–2025) · 59 papers (2020–2025)Lisa M McShane · National Cancer Institute46 papers (2020–2025)Robert Gray · University College London43 papers (2020–2025)Kurt A. Schalper · Biomarqueurs et essais cliniques en Cancérologie et Onco-Hématologie32 papers (2023–2023)Patricia LoRusso · University of California San Francisco Medical Center32 papers (2023–2023) · 32 papers (2023–2023)Diane Durecki · Yale University32 papers (2023–2023)Joseph P. Eder · Gesundheit Österreich32 papers (2023–2023)Mary Jo Pilat · Wayne State University32 papers (2023–2023) · 32 papers (2023–2023)Scott A. Boerner · University of California San Francisco Medical Center32 papers (2023–2023)Zenta Walther · Yale University32 papers (2023–2023)Michael Cecchini · Health Sciences Centre32 papers (2023–2023)Naoko Takebe · University of California San Francisco Medical Center23 papers (2018–2023) · 21 papers (2021–2023)James H. Doroshow · United States Department of Health and Human Services20 papers (2021–2023)P. Mickey Williams · Leidos (United States)19 papers (2018–2025) · 19 papers (2020–2025)