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Wei Seong Toh

National University of Singapore · SG
Area of research
Rheumatology · Genetics
Research interest
Research interests include Microvesicles, Mesenchymal stem cell, Medicine, Regeneration (biology), Cell biology, and Cartilage.
h-index
citations
6,609
works
34
NIH funding
primary concept
email

Recent publications

Therapeutic applications of cell membrane-coated nanoparticles in oral diseases: Opportunities, challenges, and future perspectives
Dental Research 2026cited by 5position: lastdoi
Therapeutic Potential of Extracellular Vesicles: From Biogenesis, Isolation and Molecular Characterization to Addressing Translational Gaps and Regulatory Barriers
International Journal of Molecular Sciences 2026cited by 3position: middledoi
Clinical Applications of Extracellular Vesicles: Promises and Pitfalls
International Journal of Molecular Sciences 2026cited by 2position: middledoi
Mitochondrial-targeted ROS scavenger delivery using selenium-doped layered double hydroxide nanocomposites for enhanced osteoarthritis therapy via inflammation suppression and macrophage metabolism reprogramming
Advanced Composites and Hybrid Materials 2026cited by 2position: middledoi
Poly(p-coumaric acid) nanoparticles alleviate temporomandibular joint osteoarthritis by inhibiting chondrocyte ferroptosis
Bioactive Materials 2024cited by 30position: middledoi
Mesenchymal Stem Cell-Based Therapies for Temporomandibular Joint Repair: A Systematic Review of Preclinical Studies
Cells 2024cited by 16position: lastdoi
Mesenchymal Stromal Cell Exosomes Mediate M2-like Macrophage Polarization through CD73/Ecto-5′-Nucleotidase Activity
Pharmaceutics 2023cited by 61position: lastdoi
Mesenchymal Stem Cell Exosomes Promote Functional Osteochondral Repair in a Clinically Relevant Porcine Model
The American Journal of Sports Medicine 2022cited by 56position: lastdoi
Macrophage Polarization as a Facile Strategy to Enhance Efficacy of Macrophage Membrane‐Coated Nanoparticles in Osteoarthritis
Small Science 2022cited by 30position: lastdoi
Critical considerations for the development of potency tests for therapeutic applications of mesenchymal stromal cell-derived small extracellular vesicles
Cytotherapy 2021cited by 234position: middledoi
Intra-articular Injections of Mesenchymal Stem Cells Without Adjuvant Therapies for Knee Osteoarthritis: A Systematic Review and Meta-analysis
The American Journal of Sports Medicine 2021cited by 61position: middledoi
Practical considerations in transforming MSC therapy for neurological diseases from cell to EV
Experimental Neurology 2021cited by 22position: middledoi
Mesenchymal stem cell exosomes in bone regenerative strategies—a systematic review of preclinical studies
Materials Today Bio 2020cited by 148position: lastdoi
International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19
Cytotherapy 2020cited by 138position: middledoi
Intra‐Articular Injections of Mesenchymal Stem Cell Exosomes and Hyaluronic Acid Improve Structural and Mechanical Properties of Repaired Cartilage in a Rabbit Model
Arthroscopy The Journal of Arthroscopic and Related Surgery 2020cited by 88position: lastdoi
Mesenchymal Stem Cell Exosomes for Cartilage Regeneration: A Systematic Review of Preclinical <i>In Vivo</i> Studies
Tissue Engineering Part B Reviews 2020cited by 79position: lastdoi
Defining mesenchymal stromal cell (MSC)‐derived small extracellular vesicles for therapeutic applications
Journal of Extracellular Vesicles 2019cited by 650position: middledoi
MSC exosomes alleviate temporomandibular joint osteoarthritis by attenuating inflammation and restoring matrix homeostasis
Biomaterials 2019cited by 560position: lastdoi
Mesenchymal stem cell exosomes enhance periodontal ligament cell functions and promote periodontal regeneration
Acta Biomaterialia 2019cited by 281position: lastdoi
Equivalent 10-Year Outcomes After Implantation of Autologous Bone Marrow–Derived Mesenchymal Stem Cells Versus Autologous Chondrocyte Implantation for Chondral Defects of the Knee
The American Journal of Sports Medicine 2019cited by 64position: middledoi
MSC exosome works through a protein-based mechanism of action
Biochemical Society Transactions 2018cited by 425position: firstdoi
Immune regulatory targets of mesenchymal stromal cell exosomes/small extracellular vesicles in tissue regeneration
Cytotherapy 2018cited by 104position: firstdoi
MSC exosomes mediate cartilage repair by enhancing proliferation, attenuating apoptosis and modulating immune reactivity
Biomaterials 2017cited by 940position: lastdoi
Concise Review: Developing Best-Practice Models for the Therapeutic Use of Extracellular Vesicles
Stem Cells Translational Medicine 2017cited by 348position: middledoi
Distribution of pericellular matrix molecules in the temporomandibular joint and their chondroprotective effects against inflammation
International Journal of Oral Science 2017cited by 49position: lastdoi
Exosomes derived from human embryonic mesenchymal stem cells promote osteochondral regeneration
Osteoarthritis and Cartilage 2016cited by 679position: lastdoi
MSC exosome as a cell-free MSC therapy for cartilage regeneration: Implications for osteoarthritis treatment
Seminars in Cell and Developmental Biology 2016cited by 514position: firstdoi
Cellular senescence in aging and osteoarthritis
Acta Orthopaedica 2016cited by 127position: firstdoi
Depth of cure of contemporary bulk-fill resin-based composites
Dental Materials Journal 2016cited by 98position: lastdoi
Advances in hydrogel delivery systems for tissue regeneration
Materials Science and Engineering C 2014cited by 177position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

Ruenn Chai Lai · National University of Singapore13 papers (2016–2023)Sai Kiang Lim · National University of Singapore13 papers (2016–2023)James Hoi Po Hui · National University of Singapore11 papers (2014–2022)Shipin Zhang · National University of Singapore9 papers (2016–2023)Keng Lin Wong · National University of Singapore6 papers (2019–2022)Kristeen Ye Wen Teo · National University of Singapore5 papers (2019–2023)Myron Spector · Massachusetts Institute of Technology4 papers (2012–2016)S. Chuah · National University of Singapore3 papers (2017–2019)Teck Chuan Lim · Massachusetts Institute of Technology3 papers (2012–2012) · 3 papers (2014–2017)Andre Choo · National University of Singapore3 papers (2019–2022)Ren Jie Jacob Chew · National University of Singapore3 papers (2019–2020) · 3 papers (2012–2012)Si Heng Sharon Tan · National University of Singapore3 papers (2020–2021) · 2 papers (2019–2021)Dominique P.V. de Kleijn · Utrecht University2 papers (2019–2021)Kenneth W. Witwer · Johns Hopkins University2 papers (2019–2021) · 2 papers (2020–2020)Hassan Afizah · National University of Singapore2 papers (2020–2022)Xiafei Ren · National University of Singapore2 papers (2020–2022)