Area of research
Infectious Diseases · Epidemiology
Research interest
Research interests include SARS-CoV-2 and COVID-19 Research, SARS-CoV-2 detection and testing, COVID-19 Clinical Research Studies, and Respiratory viral infections research.
Refined fully automated RT-qPCR assay for simultaneous detection of SARS-CoV-2, Influenza A/B, and RSV with target optimization for improved variant resilience.
Mycophenolic acid treatment drives the emergence of novel SARS-CoV-2 variants
LMP7 as a Target for Coronavirus Therapy: Inhibition by Ixazomib and Interaction with SARS-CoV-2 Proteins Nsp13 and Nsp16.
Generation and Characterization of a Tagged Recombinant SARS‐CoV‐2 for Functional Replicase Studies
Targeting a viral macrodomain: Design, Structure-Based Optimization and Antiviral Evaluation of Nanomolar Inhibitors for Mac1 of SARS-CoV-2
Inefficient tissue immune response against MPXV in an immunocompromised mpox patient
Immunity against measles, mumps, rubella, and varicella among homeless individuals in Germany — A nationwide multi-center cross-sectional study
Severe mpox in an immunocompromised patient complicated by deep tissue infection: A case report.
Analytical and clinical validation of a multiplex PCR assay for detection of <i>Neisseria gonorrhoeae</i> and <i>Chlamydia trachomatis</i> including simultaneous LGV serotyping on an automated high-throughput PCR system.
Evaluation of a Quantitative Dual-Target EBV DNA Test on a Fully Automated Molecular Testing System.
Molecular consequences of SARS-CoV-2 liver tropism
Molecular consequences of SARS-CoV-2 liver tropism.
Assessing and improving the validity of COVID-19 autopsy studies - A multicentre approach to establish essential standards for immunohistochemical and ultrastructural analyses
First report from the German COVID-19 autopsy registry
Organ manifestations of COVID-19: what have we learned so far (not only) from autopsies?
Assessing and improving the validity of COVID-19 autopsy studies - A multicentre approach to establish essential standards for immunohistochemical and ultrastructural analyses.
Clinical Evaluation of a Fully-Automated High-Throughput Multiplex Screening-Assay to Detect and Differentiate the SARS-CoV-2 B.1.1.529 (Omicron) and B.1.617.2 (Delta) Lineage Variants.
Impact of Oral Rinsing with Octenidine Based Solution on SARS-CoV-2 Loads in Saliva of Infected Patients an Exploratory Study.
Infectivity of SARS-CoV-2 on Inanimate Surfaces: Don't Trust Ct Value.
The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells
The SARS-CoV-2 main protease M<sup>pro</sup> causes microvascular brain pathology by cleaving NEMO in brain endothelial cells.
Clonal expansion and activation of tissue-resident memory-like T <sub>H</sub> 17 cells expressing GM-CSF in the lungs of patients with severe COVID-19
Clonal expansion and activation of tissue-resident memory-like Th17 cells expressing GM-CSF in the lungs of severe COVID-19 patients.
Handling and accuracy of four rapid antigen tests for the diagnosis of SARS-CoV-2 compared to RT-qPCR
Evaluation of a fully automated high-throughput SARS-CoV-2 multiplex qPCR assay with built-in screening functionality for del-HV69/70- and N501Y variants such as B.1.1.7
SARS-CoV-2 Reinfection in a Healthcare Worker Despite the Presence of Detectable Neutralizing Antibodies.
SARS-CoV-2 Blood RNA Load Predicts Outcome in Critically Ill COVID-19 Patients.
Rapid Automated Screening for SARS-CoV-2 B.1.617 Lineage Variants (Delta/Kappa) through a Versatile Toolset of qPCR-Based SNP Detection.
Clinical establishment of a laboratory developed quantitative HDV PCR assay on the cobas6800 high-throughput system.
Modifying a Diagnostic SARS-CoV-2 Spike PCR to Turn a Del69/70 Dropout into a Discriminatory On-Target Assay.