Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Cancer Genomics and Diagnostics, Genomics and Chromatin Dynamics, Bioinformatics and Genomic Networks, and Cancer-related gene regulation.
Three-dimensional genome landscape of primary human cancers
Author Correction: Patterns of somatic structural variation in human cancer genomes
Author Correction: Genomic basis for RNA alterations in cancer
Chromatin profiles classify castration-resistant prostate cancers suggesting therapeutic targets
Author Correction: Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis
Author Correction: Pathway and network analysis of more than 2500 whole cancer genomes
Author Correction: Integrative pathway enrichment analysis of multivariate omics data
Developmental chromatin programs determine oncogenic competence in melanoma
Whole-genome characterization of lung adenocarcinomas lacking alterations in the RTK/RAS/RAF pathway
Systems biology analysis of human genomes points to key pathways conferring spina bifida risk
Patterns of somatic structural variation in human cancer genomes
Passenger Mutations in More Than 2,500 Cancer Genomes: Overall Molecular Functional Impact and Consequences
Pathway and network analysis of more than 2500 whole cancer genomes
Lineage Reversion Drives WNT Independence in Intestinal Cancer
High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations
DeepMILO: a deep learning approach to predict the impact of non-coding sequence variants on 3D chromatin structure
Identification of Cancer Drivers at CTCF Insulators in 1,962 Whole Genomes
Comprehensive Characterization of Cancer Driver Genes and Mutations
FUN-LDA: A Latent Dirichlet Allocation Model for Predicting Tissue-Specific Functional Effects of Noncoding Variation: Methods and Applications
Passenger mutations in 2500 cancer genomes: Overall molecular functional impact and consequences
Abstract 1279: Passenger mutation landscape in cancer genomes
<i>MYBL1</i> rearrangements and <i>MYB</i> amplification in breast adenoid cystic carcinomas lacking the <i>MYB</i>–<i>NFIB</i> fusion gene
Discovery and characterization of coding and non-coding driver mutations in more than 2,500 whole cancer genomes
Germline determinants of the somatic mutation landscape in 2,642 cancer genomes
Role of non-coding sequence variants in cancer
LARVA: an integrative framework for large-scale analysis of recurrent variants in noncoding annotations
FunSeq2: a framework for prioritizing noncoding regulatory variants in cancer
Integrative Annotation of Variants from 1092 Humans: Application to Cancer Genomics
Architecture of the human regulatory network derived from ENCODE data
A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes