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Joseph P. Eder

Yale Cancer Center · US
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Area of research
Oncology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Lung Cancer Treatments and Mutations, Cancer therapeutics and mechanisms, Cancer Immunotherapy and Biomarkers, and Lung Cancer Research Studies.
h-index
56
citations
24,659
works
330
NIH funding
primary concept
email

Recent publications

CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials
Nature Communications 2024cited by 54position: middledoi
Developing a definition of immune exclusion in cancer: results of a modified Delphi workshop
Journal for ImmunoTherapy of Cancer 2023cited by 39position: middledoi
Influence of tumor mutational burden, inflammatory gene expression profile, and PD-L1 expression on response to pembrolizumab in head and neck squamous cell carcinoma
Journal for ImmunoTherapy of Cancer 2022cited by 95position: middledoi
BRCA2 BRC missense variants disrupt RAD51-dependent DNA repair
eLife 2022cited by 17position: middledoi
Phase I Study of Entinostat and Nivolumab with or without Ipilimumab in Advanced Solid Tumors (ETCTN-9844)
Clinical Cancer Research 2021cited by 35position: middledoi
Pembrolizumab in patients with advanced non-small-cell lung cancer (KEYNOTE-001): 3-year results from an open-label, phase 1 study
The Lancet Respiratory Medicine 2019cited by 182position: middledoi
Safety, clinical activity and biomarker assessments of atezolizumab from a Phase I study in advanced/recurrent ovarian and uterine cancers
Gynecologic Oncology 2019cited by 137position: middledoi
Long-term Clinical Outcomes and Biomarker Analyses of Atezolizumab Therapy for Patients With Metastatic Triple-Negative Breast Cancer
JAMA Oncology 2018cited by 790position: middledoi
Efficacy and safety of pembrolizumab in recurrent/metastatic head and neck squamous cell carcinoma: pooled analyses after long-term follow-up in KEYNOTE-012
British Journal of Cancer 2018cited by 449position: middledoi
Third-Line Nivolumab Monotherapy in Recurrent SCLC: CheckMate 032
Journal of Thoracic Oncology 2018cited by 376position: middledoi
Abstract LB-339: Biomarkers predictive of response to pembrolizumab in head and neck cancer (HNSCC)
Cancer Research 2018cited by 38position: middledoi
Pembrolizumab as first-line therapy for patients with PD-L1-positive advanced non-small cell lung cancer: a phase 1 trial
Annals of Oncology 2017cited by 235position: middledoi
Genomic determinants of response to pembrolizumab in head and neck squamous cell carcinoma (HNSCC).
Journal of Clinical Oncology 2017cited by 56position: middledoi
Clinical activity, safety and biomarker results from a phase Ia study of atezolizumab (atezo) in advanced/recurrent endometrial cancer (rEC).
Journal of Clinical Oncology 2017cited by 51position: middledoi
KEYNOTE-001: 3-year overall survival for patients with advanced NSCLC treated with pembrolizumab.
Journal of Clinical Oncology 2017cited by 27position: middledoi
Safety and clinical activity of pembrolizumab for treatment of recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-012): an open-label, multicentre, phase 1b trial
The Lancet Oncology 2016cited by 1,731position: middledoi
Nivolumab alone and nivolumab plus ipilimumab in recurrent small-cell lung cancer (CheckMate 032): a multicentre, open-label, phase 1/2 trial
The Lancet Oncology 2016cited by 1,252position: middledoi
Pembrolizumab for patients with PD-L1-positive advanced gastric cancer (KEYNOTE-012): a multicentre, open-label, phase 1b trial
The Lancet Oncology 2016cited by 1,130position: middledoi
Long-term OS for patients with advanced NSCLC enrolled in the KEYNOTE-001 study of pembrolizumab (pembro).
Journal of Clinical Oncology 2016cited by 61position: middledoi
Efficacy and safety of pembrolizumab in recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC): Pooled analyses after long-term follow-up in KEYNOTE-012.
Journal of Clinical Oncology 2016cited by 45position: middledoi
Biomarkers and response to pembrolizumab (pembro) in recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC).
Journal of Clinical Oncology 2016cited by 31position: middledoi
Pembrolizumab for the Treatment of Non–Small-Cell Lung Cancer
New England Journal of Medicine 2015cited by 6,195position: middledoi
Abstract 2859: Inhibition of PD-L1 by MPDL3280A leads to clinical activity in patients with metastatic triple-negative breast cancer (TNBC)
Cancer Research 2015cited by 210position: middledoi
Relationship between PD-L1 expression and clinical outcomes in patients (Pts) with advanced gastric cancer treated with the anti-PD-1 monoclonal antibody pembrolizumab (Pembro; MK-3475) in KEYNOTE-012.
Journal of Clinical Oncology 2015cited by 118position: middledoi
Inflamed-phenotype gene expression signatures to predict benefit from the anti-PD-1 antibody pembrolizumab in PD-L1+ head and neck cancer patients.
Journal of Clinical Oncology 2015cited by 55position: middledoi
Relationship between PD-L1 expression and clinical outcomes in patients with advanced gastric cancer treated with the anti-PD-1 monoclonal antibody pembrolizumab (MK-3475) in KEYNOTE-012.
Journal of Clinical Oncology 2015cited by 45position: middledoi
Correlation of gene expression signatures and clinical outcomes in patients with advanced gastric cancer treated with pembrolizumab (MK-3475).
Journal of Clinical Oncology 2015cited by 26position: middledoi
MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer
Nature 2014cited by 2,416position: middledoi
A phase Ib study of MK-3475 in patients with human papillomavirus (HPV)-associated and non-HPV–associated head and neck (H/N) cancer.
Journal of Clinical Oncology 2014cited by 128position: middledoi
Antitumor Activity of Pembrolizumab (Pembro; Mk-3475) and Correlation with Programmed Death Ligand 1 (Pd-L1) Expression in a Pooled Analysis of Patients (Pts) with Advanced Non–Small Cell Lung Carcinoma (Nsclc)
Annals of Oncology 2014cited by 72position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Jonathan D. Cheng · Southwestern Medical Center12 papers (2014–2022)Barbara Burtness · Yale University11 papers (2014–2022)Kenneth Emancipator · AbbVie (United States)10 papers (2014–2017)Laura Q.M. Chow · The University of Texas at Austin10 papers (2014–2022)Kei Muro · The University of Tokyo10 papers (2014–2022)Tanguy Y. Seiwert · University Hospital and Clinics10 papers (2014–2022)Jared Lunceford · Merck & Co., Inc., Rahway, NJ, USA (United States)9 papers (2014–2022)Jared Weiss · University of North Carolina at Chapel Hill9 papers (2014–2022)Shilpa Gupta · Vels University9 papers (2014–2022)Ravit Geva · Tel Aviv University8 papers (2014–2018)Raanan Berger · Cancer Research Center8 papers (2014–2016)Ranee Mehra · The Ohio State University8 papers (2015–2022) · 7 papers (2014–2019)Edward B. Garon · Cancer Clinic7 papers (2014–2019)Amita Patnaik · South Texas Accelerated Research Therapeutics7 papers (2014–2019) · 7 papers (2014–2015)Kumudu Pathiraja · Merck & Co., Inc., Rahway, NJ, USA (United States)7 papers (2014–2018)Rina Hui · The University of Sydney7 papers (2014–2019)Natasha B. Leighl · Princess Margaret Cancer Centre7 papers (2014–2019)Gregory M. Lubiniecki · Merck & Co., Inc., Rahway, NJ, USA (United States)7 papers (2014–2019)
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