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Astrid Gnekow

Johannes Gutenberg University Mainz · DE
🔎 Find collaborators in Genetics · Neurology →
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Area of research
Genetics · Neurology
Research interest
Research interests include Medicine, Glioma, Neurofibromatosis, DNA methylation, Chemotherapy, and Oncology.
h-index
citations
4,755
works
35
NIH funding
primary concept
email

Recent publications

The HIT Network for Children and Adolescents With CNS Tumors Facilitates Improvements of Diagnostic Assessments, Multimodal Treatments, Individual Counseling, and Research in Germany, Austria, and Switzerland
Pediatric Blood & Cancer 2026cited by 0position: middledoi
Advancing CNS tumor diagnostics with expanded DNA methylation-based classification
Cancer Cell 2025cited by 14position: middledoi
Advancing CNS tumor diagnostics with expanded DNA methylation-based classification
medRxiv 2025cited by 5position: middledoi
The HIT-network for children and adolescents with CNS tumors facilitates improvements of diagnostic assessments, multimodal treatments, individual counselling, and research in Germany, Austria, and Switzerland
2025cited by 1position: middledoi
Survivors of infant atypical teratoid/rhabdoid tumors present with severely impaired cognitive functions especially for fluid intelligence and visual processing: data from the German brain tumor studies
Pediatric Blood & Cancer 2024cited by 7position: middledoi
Adaption of neurosurgical resection patterns for pediatric low‐grade glioma spanning two decades—Report from the German <scp>LGG</scp> ‐studies 1996–2018
Cancer Medicine 2024cited by 4position: lastdoi
LGG-32. MALIGNANT TRANSFORMATION OF PEDIATRIC LOW-GRADE GLIOMA TO SECONDARY HIGH-GRADE GLIOMA - REPORT FROM THE GERMAN BRAIN TUMOR STUDIES
Neuro-Oncology 2024cited by 1position: lastdoi
Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology
Nature Medicine 2023cited by 133position: middledoi
Neurosurgical morbidity in pediatric supratentorial midline low‐grade glioma: Results from the German <scp>LGG</scp> studies
International Journal of Cancer 2023cited by 8position: middledoi
Author Correction: Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology
Nature Medicine 2023cited by 2position: middledoi
Long-term follow-up of surgical intervention pattern in pediatric low-grade gliomas: report from the German SIOP-LGG 2004 cohort
Journal of Neurosurgery Pediatrics 2022cited by 15position: middledoi
Integrated molecular and clinical analysis of low-grade gliomas in children with neurofibromatosis type 1 (NF1)
Acta Neuropathologica 2021cited by 69position: middledoi
Doubling Recruitment of Pediatric Low-grade Glioma within Two Decades does not change Outcome – Report from the German LGG Studies
Klinische Pädiatrie 2021cited by 35position: firstdoi
LGG-06. COMPREHENSIVE GENOMIC CHARACTERIZATION AND INTEGRATED CLINICAL ANALYSIS OF LOW-GRADE GLIOMAS IN CHILDREN WITH NEUROFIBROMATOSIS TYPE 1
Neuro-Oncology 2021cited by 0position: middledoi
Response to trametinib treatment in progressive pediatric low-grade glioma patients
Journal of Neuro-Oncology 2020cited by 114position: middledoi
Loss of efficacy of subsequent nonsurgical therapy after primary treatment failure in pediatric low‐grade glioma patients—Report from the German <scp>SIOP‐LGG</scp> 2004 cohort
International Journal of Cancer 2020cited by 37position: lastdoi
Long-term cognitive deficits in pediatric low-grade glioma (LGG) survivors reflect pretreatment conditions—report from the German LGG studies
Neuro-Oncology Advances 2020cited by 30position: lastdoi
Accurate calling of <i>KIAA1549‐BRAF</i> fusions from DNA of human brain tumours using methylation array‐based copy number and gene panel sequencing data
Neuropathology and Applied Neurobiology 2020cited by 19position: middledoi
High frequency of disease progression in pediatric spinal cord low-grade glioma (LGG): management strategies and results from the German LGG study group
Neuro-Oncology 2020cited by 19position: lastdoi
Prognostic impact of distinct genetic entities in pediatric diffuse glioma <scp>WHO</scp>‐grade <scp>II</scp>—Report from the German/Swiss <scp>SIOP‐LGG</scp> 2004 cohort
International Journal of Cancer 2020cited by 9position: middledoi
SIOP-E-BTG and GPOH Guidelines for Diagnosis and Treatment of Children and Adolescents with Low Grade Glioma
Klinische Pädiatrie 2019cited by 91position: firstdoi
Health status, health-related quality of life, and socioeconomic outcome in childhood brain tumor survivors: a German cohort study
Neuro-Oncology 2019cited by 26position: middledoi
Natural History of Pediatric Low-Grade Glioma Disease - First Multi-State Model Analysis
Journal of Cancer 2019cited by 23position: middledoi
Favorable prognosis in pediatric brainstem low‐grade glioma: Report from the German SIOP‐LGG 2004 cohort
International Journal of Cancer 2019cited by 18position: lastdoi
Correction: SIOP-E-BTG and GPOH Guidelines for Diagnosis and Treatment of Children and Adolescents with Low Grade Glioma
Klinische Pädiatrie 2019cited by 2position: firstdoi
DNA methylation-based classification of central nervous system tumours
Nature 2018cited by 3,091position: middledoi
THROMBOTECT – a randomized study comparing low molecular weight heparin, antithrombin and unfractionated heparin for thromboprophylaxis during induction therapy of acute lymphoblastic leukemia in children and adolescents
Haematologica 2018cited by 115position: middledoi
LGG-48. MULTI-STATE-ANALYSIS FOR PEDIATRIC PATIENTS WITH LOW-GRADE GLIOMA
Neuro-Oncology 2018cited by 0position: middledoi
Childhood cancer predisposition syndromes—A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology
American Journal of Medical Genetics Part A 2017cited by 277position: middledoi
A European randomised controlled trial of the addition of etoposide to standard vincristine and carboplatin induction as part of an 18-month treatment programme for childhood (≤16 years) low grade glioma – A final report
European Journal of Cancer 2017cited by 150position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

Torsten Pietsch · German Center for Neurodegenerative Diseases15 papers (2013–2024)Pablo Hernáiz Driever · German Center for Pediatric and Adolescent Rheumatology15 papers (2012–2024)Brigitte Bison · University of Augsburg14 papers (2012–2024)Daniela Kandels · University of Nottingham14 papers (2018–2024)Olaf Witt · St. Jude Children's Research Hospital13 papers (2018–2024)Monika Warmuth‐Metz · Universitätsklinikum Würzburg13 papers (2012–2024)Ulrich‐Wilhelm Thomale · Humboldt-Universität zu Berlin11 papers (2019–2024)Beate Timmermann · Deutschen Konsortium für Translationale Krebsforschung9 papers (2019–2022)Rolf‐Dieter Kortmann · University Medical Center8 papers (2012–2022)René Schmidt · University of Münster8 papers (2018–2024) · 5 papers (2019–2023)Martin U. Schuhmann · STZ eyetrial5 papers (2019–2024)F. Falkenstein · Johannes Gutenberg University Mainz4 papers (2012–2020)Claudia Spix · Media Working Group3 papers (2019–2024) · 3 papers (2019–2021)Ahmed El Damaty · Heidelberg University3 papers (2022–2024)Martin Benesch · Medical University of Graz3 papers (2016–2024)Michèle Simon · Humboldt-Universität zu Berlin3 papers (2020–2023) · 2 papers (2020–2024) · 2 papers (2019–2019)
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