Area of research
Genetics · Cancer Research
Research interest
Research interests include Glioma Diagnosis and Treatment, Cancer, Hypoxia, and Metabolism, ATP Synthase and ATPases Research, and Ferroptosis and cancer prognosis.
Rewiring of cortical glucose metabolism fuels human brain cancer growth
Digital twins for in vivo metabolic flux estimations in patients with brain cancer
TMET-51. EGFR metabolically suppresses differentiation in H3K27M-mutant diffuse midline glioma
GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity
Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways
Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis
GTP Signaling Links Metabolism, DNA Repair, and Responses to Genotoxic Stress
M2 isoform of pyruvate kinase rewires glucose metabolism during radiation therapy to promote an antioxidant response and glioblastoma radioresistance
A road map for the treatment of pediatric diffuse midline glioma
MRNIP condensates promote DNA double-strand break sensing and end resection
Radiation Therapy for IDH-Mutant Grade 2 and Grade 3 Diffuse Glioma: An ASTRO Clinical Practice Guideline
Development and validation of a radiopathomics model to predict pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a multicentre observational study
Epigenetically defined therapeutic targeting in H3.3G34R/V high-grade gliomas
Purine metabolism regulates DNA repair and therapy resistance in glioblastoma
Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
Everolimus improves the efficacy of dasatinib in PDGFRα-driven glioma
Phase 2 Study of a Temozolomide-Based Chemoradiation Therapy Regimen for High-Risk, Low-Grade Gliomas: Long-Term Results of Radiation Therapy Oncology Group 0424
Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy
Expression of the Androgen Receptor Governs Radiation Resistance in a Subset of Glioblastomas Vulnerable to Antiandrogen Therapy
Radiotherapy and Immunotherapy Promote Tumoral Lipid Oxidation and Ferroptosis via Synergistic Repression of SLC7A11
Androgen receptor as a mediator and biomarker of radioresistance in triple-negative breast cancer
Glioblastoma Therapy Can Be Augmented by Targeting IDH1-Mediated NADPH Biosynthesis
SBRT Provides Equivalent Local Control Compared to RFA for the Treatment of Hepatocellular Carcinoma With Minimal Toxicity