Area of research
Molecular Biology · Immunology
Research interest
Research interests include Wnt/β-catenin signaling in development and cancer, Neutrophil, Myeloperoxidase and Oxidative Mechanisms, Cell Adhesion Molecules Research, and Cancer-related gene regulation.
Human HDAC6 senses valine abundancy to regulate DNA damage.
Author Correction: Human HDAC6 senses valine abundancy to regulate DNA damage.
The CUL5 E3 ligase complex negatively regulates central signaling pathways in CD8<sup>+</sup> T cells.
LDL receptor-related protein 5 selectively transports unesterified polyunsaturated fatty acids to intracellular compartments.
Pazopanib ameliorates acute lung injuries via inhibition of MAP3K2 and MAP3K3.
Endothelial CDS2 deficiency causes VEGFA-mediated vascular regression and tumor inhibition
The plant sesquiterpene lactone parthenolide inhibits Wnt/β-catenin signaling by blocking synthesis of the transcriptional regulators TCF4/LEF1
Lanosterol Modulates TLR4-Mediated Innate Immune Responses in Macrophages
Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/β-catenin transcriptional activity
Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation
Identification of P-Rex1 as an anti-inflammatory and anti-fibrogenic target for pulmonary fibrosis
Ubl4A is required for insulin-induced Akt plasma membrane translocation through promotion of Arp2/3-dependent actin branching
Clathrin and AP2 are required for PtdIns(4,5)P2-mediated formation of LRP6 signalosomes
PRR5L degradation promotes mTORC2-mediated PKC-δ phosphorylation and cell migration downstream of Gα12
A Critical Role for Phosphatidylinositol (3,4,5)-Trisphosphate–Dependent Rac Exchanger 1 in Endothelial Junction Disruption and Vascular Hyperpermeability