Area of research
Cellular and Molecular Neuroscience · Developmental Neuroscience
Research interest
Research interests include Axon Guidance and Neuronal Signaling, Neurogenesis and neuroplasticity mechanisms, Glioma Diagnosis and Treatment, and Nerve injury and regeneration.
AhR inhibition promotes axon regeneration via a stress–growth switch
Directional guidance to orient Schwann cell alignment in nerve regeneration requires Plexin-B1
Glioblastoma shift from bulk to infiltrative growth is guided by plexin-B2-mediated microglia alignment in invasive niches
Invasion of glioma cells through confined space requires membrane tension regulation and mechano-electrical coupling via Plexin-B2
PLXNB1 and other signaling drives a pathologic astrocyte state contributing to cognitive decline in Alzheimer’s Disease
3D Brain Vascular Niche Model Captures Glioblastoma Infiltration, Dormancy, and Gene Signatures
Plexin-B1 safeguards astrocyte agility and glial alignment to facilitate wound corralling and axon pathfinding in mouse spinal cord injury model
Generation of Plexin‐ <scp>B1</scp> Conditional Knockout Mouse With <scp>CRISPR</scp> /Cas9 Technology
Cortical tension as a mechanical barrier to safeguard against premature differentiation during neurogenesis
Regulation of cell distancing in peri-plaque glial nets by Plexin-B1 affects glial activation and amyloid compaction in Alzheimer’s disease
Hypoxia drives shared and distinct transcriptomic changes in two invasive glioma stem cell lines
Repression of the SUMO-conjugating enzyme UBC9 is associated with lowered double minutes and reduced tumor progression
Invasion of glioma cells through confined space requires membrane tension regulation and mechano-electrical coupling via Plexin-B2
3D Brain Vascular Niche Model Captures Invasive Behavior and Gene Signatures of Glioblastoma
Hypoxic niches attract and sequester tumor-associated macrophages and cytotoxic T cells and reprogram them for immunosuppression
Circadian clock regulator Bmal1 gates axon regeneration via Tet3 epigenetics in mouse sensory neurons
Alveolar Macrophages-Mediated Translocation of Intratracheally Delivered Perfluorocarbon Nanoparticles to Achieve Lung Cancer <sup>19</sup>F-MR Imaging
c-Met-Targeting 19F MRI Nanoparticles with Ultralong Tumor Retention for Precisely Detecting Small or Ill-Defined Colorectal Liver Metastases
AhR restricts axon regeneration by balancing neuronal stress and growth response after injury
Pulmonary Delivery of Theranostic Nanoclusters for Lung Cancer Ferroptosis with Enhanced Chemodynamic/Radiation Synergistic Therapy
Macrophages facilitate peripheral nerve regeneration by organizing regeneration tracks through Plexin-B2
An Osimertinib-Perfluorocarbon Nanoemulsion with Excellent Targeted Therapeutic Efficacy in Non-small Cell Lung Cancer: Achieving Intratracheal and Intravenous Administration
Magnetic Resonance/Infrared Dual-Modal Imaging-Guided Synergistic Photothermal/Photodynamic Therapy Nanoplatform Based on Cu1.96S-Gd@FA for Precision Cancer Theranostics
Spatial patterning and immunosuppression of glioblastoma immune contexture in hypoxic niches
Diversified transcriptional responses of myeloid and glial cells in spinal cord injury shaped by HDAC3 activity
Plexin-B2 orchestrates collective stem cell dynamics via actomyosin contractility, cytoskeletal tension and adhesion
Plexin-B2 facilitates glioblastoma infiltration by modulating cell biomechanics
Evolution and Diversity of Semaphorins and Plexins in Choanoflagellates
Microglia and macrophages promote corralling, wound compaction and recovery after spinal cord injury via Plexin-B2
High-resolution tomographic analysis of in vitro 3D glioblastoma tumor model under long-term drug treatment