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James Brugarolas

Southwestern Medical Center · US
Area of research
Pulmonary and Respiratory Medicine · Molecular Biology
Research interest
Research interests include Renal cell carcinoma, Medicine, Biology, Cancer research, Carcinogenesis, and Cancer.
h-index
citations
3,039
works
25
NIH funding
primary concept
email

Recent publications

Glycosaminoglycan-driven lipoprotein uptake protects tumours from ferroptosis
Nature 2025cited by 36position: middledoi
A Call for a Neoadjuvant Kidney Cancer Consortium: Lessons Learned from Other Cancer Types
European Urology 2025cited by 10position: middledoi
BBOX1 restrains TBK1-mTORC1 oncogenic signaling in clear cell renal cell carcinoma
Nature Communications 2025cited by 7position: middledoi
De novo and salvage purine synthesis pathways across tissues and tumors
Cell 2024cited by 154position: middledoi
Comparative genomics incorporating translocation renal cell carcinoma mouse model reveals molecular mechanisms of tumorigenesis
Journal of Clinical Investigation 2024cited by 27position: lastdoi
Molecular analysis of primary and metastatic sites in patients with renal cell carcinoma
Journal of Clinical Investigation 2024cited by 25position: middledoi
GPR1 and CMKLR1 Control Lipid Metabolism to Support the Development of Clear Cell Renal Cell Carcinoma
Cancer Research 2024cited by 23position: middledoi
Randomized phase II dose comparison LITESPARK-013 study of belzutifan in patients with advanced clear cell renal cell carcinoma
Annals of Oncology 2024cited by 14position: middledoi
Molecular underpinnings of dedifferentiation and aggressiveness in chromophobe renal cell carcinoma
JCI Insight 2024cited by 14position: lastdoi
Kinome-wide siRNA screen identifies a DCLK2-TBK1 oncogenic signaling axis in clear cell renal cell carcinoma
Molecular Cell 2024cited by 10position: middledoi
Metastatic renal cell carcinoma to the pancreas and other sites—a multicenter retrospective study
EClinicalMedicine 2023cited by 23position: middledoi
In vivo characterization of glutamine metabolism identifies therapeutic targets in clear cell renal cell carcinoma
Science Advances 2022cited by 57position: middledoi
An interdisciplinary consensus on the management of brain metastases in patients with renal cell carcinoma
CA A Cancer Journal for Clinicians 2022cited by 34position: middledoi
Neoadjuvant SABR for Renal Cell Carcinoma Inferior Vena Cava Tumor Thrombus—Safety Lead-in Results of a Phase 2 Trial
International Journal of Radiation Oncology*Biology*Physics 2021cited by 71position: middledoi
A renal cell carcinoma tumorgraft platform to advance precision medicine
Cell Reports 2021cited by 55position: lastdoi
Genetic risk assessment for hereditary renal cell carcinoma: Clinical consensus statement
Cancer 2021cited by 44position: middledoi
Biological Mechanisms and Clinical Significance of <i>BAP1</i> Mutations in Human Cancer
Cancer Discovery 2020cited by 283position: middledoi
Familial Kidney Cancer: Implications of New Syndromes and Molecular Insights
European Urology 2019cited by 115position: middledoi
The complex relationship between <scp>TFEB</scp> transcription factor phosphorylation and subcellular localization
The EMBO Journal 2018cited by 520position: middledoi
An Empirical Approach Leveraging Tumorgrafts to Dissect the Tumor Microenvironment in Renal Cell Carcinoma Identifies Missing Link to Prognostic Inflammatory Factors
Cancer Discovery 2018cited by 183position: lastdoi
Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine
Cell Death and Differentiation 2018cited by 36position: middledoi
Targeting renal cell carcinoma with a HIF-2 antagonist
Nature 2016cited by 716position: lastdoi
Spectrum of diverse genomic alterations define non–clear cell renal carcinoma subtypes
Nature Genetics 2014cited by 357position: middledoi
Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes
Nature Immunology 2012cited by 140position: middledoi
Metabolism of Kidney Cancer: From the Lab to Clinical Practice
European Urology 2012cited by 85position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Payal Kapur · Southwestern Medical Center5 papers (2021–2025)Hua Zhong · National University of Singapore4 papers (2024–2025)Vanina Toffessi Tcheuyap · Maryland Oncology Hematology3 papers (2024–2024)Dinesh Rakheja · Southwestern Medical Center3 papers (2012–2024)Jin Zhou · The University of Texas Southwestern Medical Center2 papers (2024–2025)Lin Xu · Tongji University2 papers (2024–2025)Vitaly Margulis · Creative Commons2 papers (2012–2021)Qing Zhang · Gannon University2 papers (2024–2025)Hongyi Liu · The University of Texas Southwestern Medical Center2 papers (2024–2025)W. Marston Linehan · National Institutes of Health2 papers (2012–2019)Deyssy Carrillo · Southwestern Medical Center2 papers (2024–2024)Jun Fang · Southwestern Medical Center2 papers (2024–2025)Chengheng Liao · Southwestern Medical Center2 papers (2024–2025)Ralph J. DeBerardinis · Children's Medical Center2 papers (2024–2025)Lei Guo · Wenzhou Medical University2 papers (2024–2025)Jeffrey Miyata · Southwestern Medical Center2 papers (2024–2024)Hongwei Yao · Xi'an Jiaotong University2 papers (2024–2025)Alana Christie · Southwestern Medical Center2 papers (2021–2024)Steffen Durinck · Gene Therapy Laboratory2 papers (2024–2024)Iván Pedrosa · The University of Texas Southwestern Medical Center2 papers (2021–2024)