Area of research
Molecular Biology · Oncology
Research interest
Research interests include S100 Proteins and Annexins, Cancer Cells and Metastasis, Cancer Genomics and Diagnostics, and Cancer Research and Treatments.
MACC1 Expression in Colorectal Cancer Is Upregulated by Loss of Epigenetic Repression Under Oxidative Stress Condition
EPI-X4, a CXCR4 antagonist inhibits tumor growth in pancreatic cancer and lymphoma models
EPI-X4, a CXCR4 Antagonist Inhibits Tumor Growth in Pancreatic Cancer and Lymphoma Models
Calcium-binding protein S100P is a new target gene of MACC1, drives colorectal cancer metastasis and serves as a prognostic biomarker
Combinatorial treatment with statins and niclosamide prevents CRC dissemination by unhinging the MACC1-β-catenin-S100A4 axis of metastasis
Core-Clock Genes Regulate Proliferation and Invasion via a Reciprocal Interplay with MACC1 in Colorectal Cancer Cells
MACC1-Induced Collective Migration Is Promoted by Proliferation Rather Than Single Cell Biomechanics
S100A4 Is a Strong Negative Prognostic Marker and Potential Therapeutic Target in Adenocarcinoma of the Stomach and Esophagus
A Molecularly Characterized Preclinical Platform of Subcutaneous Renal Cell Carcinoma (RCC) Patient-Derived Xenograft Models to Evaluate Novel Treatment Strategies
MACC1 regulates clathrin-mediated endocytosis and receptor recycling of transferrin receptor and EGFR in colorectal cancer
The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis
Combination of Wnt/β-Catenin Targets S100A4 and DKK1 Improves Prognosis of Human Colorectal Cancer
Peritoneal metastasis of colorectal cancer (pmCRC): identification of predictive molecular signatures by a novel preclinical platform of matching pmCRC PDX/PD3D models
A Bioinformatic Pipeline to Identify Biomarkers for Metastasis Formation from RNA Sequencing Data
Restoring Treatment Response in Colorectal Cancer Cells by Targeting MACC1-Dependent ABCB1 Expression in Combination Therapy
MACC1 driven alterations in cellular biomechanics facilitate cell motility in glioblastoma
Small Ones to Fight a Big Problem—Intervention of Cancer Metastasis by Small Molecules
Pressurized intraperitoneal aerosol chemotherapy and its effect on gastric-cancer-derived peritoneal metastases: an overview
Circulating MACC1 Transcripts in Glioblastoma Patients Predict Prognosis and Treatment Response
MACC1—the first decade of a key metastasis molecule from gene discovery to clinical translation
Expression of activating transcription factor 5 (ATF5) is increased in astrocytomas of different WHO grades and correlates with survival of glioblastoma patients
Abstract 4099: Novel patient-derived 3D (PD3D) cell models and matched patient-derived xenografts (PDX) from peritoneal metastasis of colorectal cancer for drug testing and biomarker analysis
Statin and rottlerin small-molecule inhibitors restrict colon cancer progression and metastasis via MACC1
MACC1, a Novel Player in Solid Cancer Carcinogenesis
S100A4 is related to an invasive phenotype and a poor outcome in patients with adenocarcinoma of the stomach and esophagus
S100A4 in Cancer Metastasis: Wnt Signaling-Driven Interventions for Metastasis Restriction
SPON2, a newly identified target gene of MACC1, drives colorectal cancer metastasis in mice and is prognostic for colorectal cancer patient survival