Area of research
Molecular Biology · Neurology
Research interest
Research interests include Disease, PRNP, Cerebrospinal fluid, Biology, Pathology, and Medicine.
In vivo base editing extends lifespan of a humanized mouse model of prion disease
Large-scale validation of skin prion seeding activity as a biomarker for diagnosis of prion diseases
Genome‐wide association studies identify novel loci in rapidly progressive Alzheimer's disease
Neuropathologically directed profiling of PRNP somatic and germline variants in sporadic human prion disease
Distinct conformers of amyloid beta accumulate in the neocortex of patients with rapidly progressive Alzheimer's disease
Phosphorylated tau interactome in the human Alzheimer’s disease brain
Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study
Ring trial of 2nd generation RT‐QuIC diagnostic tests for sporadic CJD
Age at onset in genetic prion disease and the design of preventive clinical trials
Prion protein quantification in human cerebrospinal fluid as a tool for prion disease drug development
Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC
Prion Seeds Distribute throughout the Eyes of Sporadic Creutzfeldt-Jakob Disease Patients
Proteomic differences in amyloid plaques in rapidly progressive and sporadic Alzheimer’s disease
Prion seeding activity and infectivity in skin samples from patients with sporadic Creutzfeldt-Jakob disease