Area of research
Molecular Biology · Materials Chemistry
Research interest
Research interests include Metal complexes synthesis and properties, Advanced biosensing and bioanalysis techniques, DNA and Nucleic Acid Chemistry, and Crystallization and Solubility Studies.
Evoking Simultaneous Ferroptosis and Apoptosis by a Dual‐Locked Platinum (IV) Prodrug for Synergistic Chemo‐immunotherapy
Targeting the Adenosine‐Mediated Metabolic Immune Checkpoint with Engineered Probiotic for Enhanced Chemo‐Immunotherapy
Photoinduction of Ferroptosis and cGAS-STING Activation by a H<sub>2</sub>S-Responsive Iridium(III) Complex for Cancer-Specific Therapy
G-quadruplex-guided cisplatin triggers multiple pathways in targeted chemotherapy and immunotherapy
Ruthenium(ii)–Arene Complex Triggers Immunogenic Ferroptosis for Reversing Drug Resistance
Platinum‐Metformin Conjugates Acting as Promising PD‐L1 Inhibitors through the AMP‐Activated Protein Kinase Mediated Lysosomal Degradation Pathway
Aggregation-Induced Emission (AIE), Life and Health
Organometallic anti-tumor agents: targeting from biomolecules to dynamic bioprocesses
Engineered Bacteria Labeled with Iridium(III) Photosensitizers for Enhanced Photodynamic Immunotherapy of Solid Tumors
Evoking Ferroptosis by Synergistic Enhancement of a Cyclopentadienyl Iridium‐Betulin Immune Agonist
Organic‐Platinum Hybrids for Covalent Binding of G‐Quadruplexes: Structural Basis and Application to Cancer Immunotherapy
A Golgi‐Targeted Platinum Complex Plays a Dual Role in Autophagy Regulation for Highly Efficient Cancer Therapy
Simultaneous Photoactivation of cGAS‐STING Pathway and Pyroptosis by Platinum(II) Triphenylamine Complexes for Cancer Immunotherapy
Ru(II)-modified TiO2 nanoparticles for hypoxia-adaptive photo-immunotherapy of oral squamous cell carcinoma
A Nuclear‐Targeted AIE Photosensitizer for Enzyme Inhibition and Photosensitization in Cancer Cell Ablation
Structural Basis of Pyridostatin and Its Derivatives Specifically Binding to G-Quadruplexes
Disruption of Zinc Homeostasis by a Novel Platinum(IV)‐Terthiophene Complex for Antitumor Immunity
Self‐Amplifying Iridium(III) Photosensitizer for Ferroptosis‐Mediated Immunotherapy Against Transferrin Receptor‐Overexpressing Cancer
In Situ Prodrug Activation by an Affibody‐Ruthenium Catalyst Hybrid for HER2‐Targeted Chemotherapy
Inhibition of Quorum-Sensing Regulator from Pseudomonas aeruginosa Using a Flavone Derivative
A Polarity‐Sensitive Ratiometric Fluorescence Probe for Monitoring Changes in Lipid Droplets and Nucleus during Ferroptosis
A Carbonic Anhydrase IX (CAIX)‐Anchored Rhenium(I) Photosensitizer Evokes Pyroptosis for Enhanced Anti‐Tumor Immunity
Ferroptosis‐Enhanced Cancer Immunity by a Ferrocene‐Appended Iridium(III) Diphosphine Complex
Phosphorescent metal complexes as theranostic anticancer agents: combining imaging and therapy in a single molecule
Light‐Driven Cascade Mitochondria‐to‐Nucleus Photosensitization in Cancer Cell Ablation
Induction and Monitoring of DNA Phase Separation in Living Cells by a Light-Switching Ruthenium Complex
Approaches towards understanding the mechanism-of-action of metallodrugs
Photoactivated Osmium Arene Anticancer Complexes
CAIXplatins: Highly Potent Platinum(IV) Prodrugs Selective Against Carbonic Anhydrase IX for the Treatment of Hypoxic Tumors
Quantitative Detection of G‐Quadruplex DNA in Live Cells Based on Photon Counts and Complex Structure Discrimination