Area of research
Genetics · Cancer Research
Research interest
Research interests include Glioma Diagnosis and Treatment, Cancer, Hypoxia, and Metabolism, ATP Synthase and ATPases Research, and Mass Spectrometry Techniques and Applications.
Characterization of a pathogenic subpopulation of human glioma associated macrophages linked to glioma progression
Rewiring of cortical glucose metabolism fuels human brain cancer growth
A window-of-opportunity trial reveals mechanisms of response and resistance to navtemadlin in patients with recurrent glioblastoma
Serial multiomics uncovers anti-glioblastoma responses not evident by routine clinical analyses
Phase I Study of Adavosertib with Radiotherapy and Temozolomide in Newly Diagnosed Glioblastoma and Intratumoral Drug Levels in Recurrent Glioblastoma
Nitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice
TMIC-70. Integrative spatiotemporal proteomic and metabolomic characterization of immune infiltration following intracranial injection of oncolytic immunotherapy in glioblastoma patients
DNA damage response in brain tumors: A Society for Neuro-Oncology consensus review on mechanisms and translational efforts in neuro-oncology
Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS
Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways
Oncometabolite <scp>d</scp> -2HG alters T cell metabolism to impair CD8 <sup>+</sup> T cell function
De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma
BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma
PARP-inhibition reprograms macrophages toward an anti-tumor phenotype
LTBK-04. LATE BREAKING ABSTRACT: MEK162 (binimetinib) in children with progressive or recurrent low-grade glioma: a multi-institutional phase II and target validation study
Heterogeneous delivery across the blood-brain barrier limits the efficacy of an EGFR-targeting antibody drug conjugate in glioblastoma
Multimodal platform for assessing drug distribution and response in clinical trials
Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial
Localized Metabolomic Gradients in Patient-Derived Xenograft Models of Glioblastoma
Automatic 3D Nonlinear Registration of Mass Spectrometry Imaging and Magnetic Resonance Imaging Data
Blood–brain-barrier organoids for investigating the permeability of CNS therapeutics
Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma
Rapid discrimination of pediatric brain tumors by mass spectrometry imaging
Is the blood–brain barrier really disrupted in all glioblastomas? A critical assessment of existing clinical data
Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents
Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma
Osteoglycin promotes meningioma development through downregulation of NF2 and activation of mTOR signaling
Intraoperative mass spectrometry mapping of an onco-metabolite to guide brain tumor surgery
Application of desorption electrospray ionization mass spectrometry imaging in breast cancer margin analysis
ET-24 * A NOVEL TROJAN HORSE FOR IN-VIVO SENSITIVITY TESTING OF MEDULLOBLASTOMA THERAPIES