Area of research
Molecular Biology · Rheumatology
Research interest
Research interests include Inflammasome and immune disorders, Systemic Lupus Erythematosus Research, Palliative Care and End-of-Life Issues, and Synthesis and biological activity.
Cyclical palmitoylation regulates TLR9 signalling and systemic autoimmunity in mice
Tfh cells with NLRP3 inflammasome activation are essential for high-affinity antibody generation, germinal centre formation and autoimmunity
Pathogenesis of lupus nephritis: RIP3 dependent necroptosis and NLRP3 inflammasome activation
Pim‐1 as a Therapeutic Target in Lupus Nephritis
NLRP3 inflammasome activation contributes to the pathogenesis of rheumatoid arthritis
Podocyte Activation of NLRP3 Inflammasomes Contributes to the Development of Proteinuria in Lupus Nephritis
The ratio of circulating follicular T helper cell to follicular T regulatory cell is correlated with disease activity in systemic lupus erythematosus
Anti-dsDNA antibodies bind to TLR4 and activate NLRP3 inflammasome in lupus monocytes/macrophages
Myeloid-derived suppressor cells are proinflammatory and regulate collagen-induced arthritis through manipulating Th17 cell differentiation
P2X<sub>7</sub> Blockade Attenuates Murine Lupus Nephritis by Inhibiting Activation of the NLRP3/ASC/Caspase 1 Pathway
Bay11-7082 attenuates murine lupus nephritis via inhibiting NLRP3 inflammasome and NF-κB activation