Area of research
Molecular Biology · Neurology
Research interest
Research interests include RNA Research and Splicing, Amyotrophic Lateral Sclerosis Research, Neurogenetic and Muscular Disorders Research, and RNA and protein synthesis mechanisms.
The Structured RNA-binding Domains and Condensation Capacity of FUS Shape its RNA-binding Landscape and Function
Single-cell RNA-sequencing reveals early mitochondrial dysfunction unique to motor neurons shared across FUS- and TARDBP-ALS
Cognition on the move: Examining the role of physical exercise and neurogenesis in counteracting cognitive aging
Molecular basis of RNA-binding and autoregulation by the cancer-associated splicing factor RBM39
HNRNPH1 regulates the neuroprotective cold‐shock protein RBM3 expression through poison exon exclusion
G-quadruplexes control hepatitis B virus replication by promoting cccDNA transcription and phase separation in hepatocytes
FUS-dependent liquid–liquid phase separation is important for DNA repair initiation
The phase separation-dependent FUS interactome reveals nuclear and cytoplasmic function of liquid–liquid phase separation
FUS ALS-causative mutations impair FUS autoregulation and splicing factor networks through intron retention
Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis
miR-129-5p: A key factor and therapeutic target in amyotrophic lateral sclerosis
Human vtRNA1-1 Levels Modulate Signaling Pathways and Regulate Apoptosis in Human Cancer Cells
Targeting CD47 in Anaplastic Thyroid Carcinoma Enhances Tumor Phagocytosis by Macrophages and Is a Promising Therapeutic Strategy
Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization
Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation
Hypertonic Stress Causes Cytoplasmic Translocation of Neuronal, but Not Astrocytic, FUS due to Impaired Transportin Function
CRISPR-Trap: a clean approach for the generation of gene knockouts and gene replacements in human cells