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Jason M. Sheltzer

Palo Alto University · US
Area of research
Cancer Research · Genetics
Research interest
Research interests include Cancer Genomics and Diagnostics, Microtubule and mitosis dynamics, CRISPR and Genetic Engineering, and Genomic variations and chromosomal abnormalities.
h-index
28
citations
5,318
works
103
NIH funding
primary concept
email

Recent publications

Protein buffering of aneuploidy is driven by coordinated factors identified through machine learning
Molecular Systems Biology 2026cited by 2position: middledoi
Paired CRISPR screens identify mitochondrial metabolism and UBE2H as aneuploid-specific dependencies in human cancer cell lines
bioRxiv (Cold Spring Harbor Laboratory) 2026cited by 0position: lastdoi
Oncogene-like addiction to aneuploidy in human cancers
Science 2023cited by 159position: lastdoi
Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity
EBioMedicine 2021cited by 397position: middledoi
Cigarette Smoke Exposure and Inflammatory Signaling Increase the Expression of the SARS-CoV-2 Receptor ACE2 in the Respiratory Tract
Developmental Cell 2020cited by 420position: lastdoi
Aneuploidy increases resistance to chemotherapeutics by antagonizing cell division
Proceedings of the National Academy of Sciences 2020cited by 115position: middledoi
Single-Chromosomal Gains Can Function as Metastasis Suppressors and Promoters in Colon Cancer
Developmental Cell 2020cited by 108position: lastdoi
Discovering and validating cancer genetic dependencies: approaches and pitfalls
Nature Reviews Genetics 2020cited by 62position: lastdoi
Generating Single Cell–Derived Knockout Clones in Mammalian Cells with CRISPR/Cas9
Current Protocols in Molecular Biology 2019cited by 136position: lastdoi
Single-chromosome Gains Commonly Function as Tumor Suppressors
Cancer Cell 2017cited by 211position: firstdoi
Mitotic entry in the presence of DNA damage is a widespread property of aneuploidy in yeast
Molecular Biology of the Cell 2015cited by 41position: middledoi
A Transcriptional and Metabolic Signature of Primary Aneuploidy Is Present in Chromosomally Unstable Cancer Cells and Informs Clinical Prognosis
Cancer Research 2013cited by 107position: firstdoi
Transcriptional consequences of aneuploidy
Proceedings of the National Academy of Sciences 2012cited by 318position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

· 4 papers (2020–2023)Angelika Amon · Massachusetts Institute of Technology4 papers (2012–2020)Vishruth Girish · Johns Hopkins Medicine3 papers (2019–2023) · 3 papers (2020–2023)Erin L. Sausville · Yale Cancer Center3 papers (2020–2026)Zuzana Štorchová · Ludwig-Maximilians-Universität München3 papers (2017–2026)Colleen M. Meehl · Howard Hughes Medical Institute2 papers (2015–2017)Klaske M. Schukken · Palo Alto University2 papers (2023–2026)Monet Lou Yuan · Cold Spring Harbor Laboratory2 papers (2020–2023)Charles Zou · Yale Cancer Center2 papers (2023–2026)Pranav K. Kandikuppa · Yale Cancer Center2 papers (2023–2026)Saron M. Akalu · University of California, Berkeley2 papers (2023–2026)John Replogle · National Institutes of Health2 papers (2017–2020)Ann Lin · University of South Florida2 papers (2019–2020)Nicole M. Sayles · Cornell University2 papers (2017–2020) · 1 papers (2021–2021)Ole S. Søgaard · Aarhus University1 papers (2021–2021) · 1 papers (2026–2026)Armin Braun · Medizinische Hochschule Hannover1 papers (2021–2021)Frank Noé · University of California, Berkeley1 papers (2021–2021)