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John E. McDonough

KU Leuven · BE
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Area of research
Pulmonary and Respiratory Medicine · Radiation
Research interest
Research interests include Medicine, Lung, Pathology, COPD, Fibrosis, and Idiopathic pulmonary fibrosis.
h-index
citations
2,701
works
28
NIH funding
primary concept
email

Recent publications

Single-cell atlas of human lung aging identifies cell type dyssynchrony and increased transcriptional entropy
Nature Communications 2026cited by 4position: middledoi
A deep generative model for deciphering cellular dynamics and in silico drug discovery in complex diseases
Nature Biomedical Engineering 2025cited by 16position: middledoi
Computational fluid dynamics of small airway disease in chronic obstructive pulmonary disease
EBioMedicine 2025cited by 9position: middledoi
microRNA-33 deficiency in macrophages enhances autophagy, improves mitochondrial homeostasis, and protects against lung fibrosis
JCI Insight 2023cited by 59position: middledoi
Mucosal immune alterations at the early onset of tissue destruction in chronic obstructive pulmonary disease
Frontiers in Immunology 2023cited by 21position: middledoi
Characterization of the COPD alveolar niche using single-cell RNA sequencing
Nature Communications 2022cited by 219position: middledoi
The transition from normal lung anatomy to minimal and established fibrosis in idiopathic pulmonary fibrosis (IPF)
EBioMedicine 2021cited by 46position: middledoi
IGF1R is an entry receptor for respiratory syncytial virus
Nature 2020cited by 208position: middledoi
Small airways pathology in idiopathic pulmonary fibrosis: a retrospective cohort study
The Lancet Respiratory Medicine 2020cited by 123position: middledoi
Vitamin D Metabolism is Dysregulated in Asthma and Chronic Obstructive Pulmonary Disease
American Journal of Respiratory and Critical Care Medicine 2020cited by 85position: middledoi
Small airway loss in the physiologically ageing lung: a cross-sectional study in unused donor lungs
The Lancet Respiratory Medicine 2020cited by 60position: middledoi
Pathology of Idiopathic Pulmonary Fibrosis Assessed by a Combination of Microcomputed Tomography, Histology, and Immunohistochemistry
American Journal Of Pathology 2020cited by 50position: middledoi
Publisher Correction: IGF1R is an entry receptor for respiratory syncytial virus
Nature 2020cited by 8position: middledoi
Transcriptional regulatory model of fibrosis progression in the human lung
JCI Insight 2019cited by 183position: firstdoi
Computed Tomography Total Airway Count Is Associated with the Number of Micro–Computed Tomography Terminal Bronchioles
American Journal of Respiratory and Critical Care Medicine 2019cited by 43position: middledoi
Influence of azithromycin and allograft rejection on the post–lung transplant microbiota
The Journal of Heart and Lung Transplantation 2019cited by 40position: middledoi
Gene correlation network analysis to identify regulatory factors in idiopathic pulmonary fibrosis
Thorax 2018cited by 65position: firstdoi
The aging lung: tissue telomere shortening in health and disease
Respiratory Research 2018cited by 59position: middledoi
A role for telomere length and chromosomal damage in idiopathic pulmonary fibrosis
Respiratory Research 2018cited by 50position: firstdoi
The cellular and molecular determinants of emphysematous destruction in COPD
Scientific Reports 2017cited by 65position: middledoi
Thin-Section CT Features of Idiopathic Pulmonary Fibrosis Correlated with Micro-CT and Histologic Analysis
Radiology 2016cited by 84position: middledoi
Micro–Computed Tomography Comparison of Preterminal Bronchioles in Centrilobular and Panlobular Emphysema
American Journal of Respiratory and Critical Care Medicine 2016cited by 60position: middledoi
Host Response to the Lung Microbiome in Chronic Obstructive Pulmonary Disease
American Journal of Respiratory and Critical Care Medicine 2015cited by 252position: middledoi
Morphometric Analysis of Explant Lungs in Cystic Fibrosis
American Journal of Respiratory and Critical Care Medicine 2015cited by 68position: middledoi
Linking clinical phenotypes of chronic lung allograft dysfunction to changes in lung structure
European Respiratory Journal 2015cited by 55position: middledoi
The Site and Nature of Airway Obstruction after Lung Transplantation
American Journal of Respiratory and Critical Care Medicine 2014cited by 89position: middledoi
The Lung Tissue Microbiome in Chronic Obstructive Pulmonary Disease
American Journal of Respiratory and Critical Care Medicine 2012cited by 550position: middledoi
A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK
Genome Medicine 2012cited by 130position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

James C. Hogg · University of British Columbia16 papers (2012–2021)Bart Vanaudenaerde · KU Leuven15 papers (2014–2026)Stijn E. Verleden · University of Antwerp12 papers (2014–2021)Joel D. Cooper · California University of Pennsylvania11 papers (2012–2021)Wim Wuyts · Medizinische Hochschule Hannover10 papers (2015–2026)Geert M. Verleden · Antwerp University Hospital9 papers (2014–2020)Dragoş M. Vasilescu · University of Iowa7 papers (2014–2021)Johny Verschakelen · Université Libre de Bruxelles7 papers (2014–2021) · 6 papers (2016–2021)Robin Vos · KU Leuven6 papers (2014–2025)Dirk Van Raemdonck · KU Leuven6 papers (2014–2020)Naftali Kaminski · Yale University5 papers (2018–2025)Erik Verbeken · VIB-KU Leuven Center for Microbiology5 papers (2014–2020)Tillie‐Louise Hackett · University of British Columbia Hospital4 papers (2012–2021) · 4 papers (2012–2017)Marc E. Lenburg · Boston University4 papers (2012–2021)Marc Decramer · University of British Columbia4 papers (2014–2020)Feng Xu · Fudan University3 papers (2020–2021)Laurens De Sadeleer · KU Leuven3 papers (2018–2025)Joshua D. Campbell · Broad Institute3 papers (2012–2017)
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