Area of research
Molecular Biology · Genetics
Research interest
Research interests include Medicine, Internal medicine, Mendelian randomization, Biology, Cohort, and Dementia.
Remote cognitive tests predict neurodegenerative biomarkers in the Insight 46 cohort
Cigarette Smoking and E-cigarette Use Induce Shared DNA Methylation Changes Linked to Carcinogenesis
Updating the study protocol: Insight 46 – a longitudinal neuroscience sub-study of the MRC National Survey of Health and Development – phases 2 and 3
Associations between accelerated forgetting, amyloid deposition and brain atrophy in older adults
Rates of cortical thinning in Alzheimer’s disease signature regions associate with vascular burden but not with β-amyloid status in cognitively normal adults at age 70
Genetic impacts on DNA methylation help elucidate regulatory genomic processes
Antibody levels following vaccination against SARS-CoV-2: associations with post-vaccination infection and risk factors in two UK longitudinal studies
Biomedical consequences of elevated cholesterol-containing lipoproteins and apolipoproteins on cardiovascular and non-cardiovascular outcomes
Neuroimaging, clinical and life course correlates of normal-appearing white matter integrity in 70-year-olds
Methodology dependent sex differences in Aβ‐PET measured with SUVR
Associations between peripheral hearing ability at age 70, brain atrophy and cognitive decline in adults born in the same week of 1946
Life course, genetic, and neuropathological associations with brain age in the 1946 British Birth Cohort: a population-based study
Adulthood cognitive trajectories over 26 years and brain health at 70 years of age: findings from the 1946 British Birth Cohort
Cholesteryl ester transfer protein (CETP) as a drug target for cardiovascular disease
Novel DNA methylation signatures of tobacco smoking with trans-ethnic effects
Mendelian randomization identifies blood metabolites previously linked to midlife cognition as causal candidates in Alzheimer’s disease
Dissociable effects of APOE ε4 and β-amyloid pathology on visual working memory
Investigating the relationship between BMI across adulthood and late life brain pathologies
Visuomotor integration deficits are common to familial and sporadic preclinical Alzheimer’s disease
A population‐based study of head injury, cognitive function and pathological markers
The Dementias Platform UK (DPUK) Data Portal
Increased variability in reaction time is associated with amyloid beta pathology at age 70
Amyloid β influences the relationship between cortical thickness and vascular load
Olfactory testing does not predict β-amyloid, MRI measures of neurodegeneration or vascular pathology in the British 1946 birth cohort
APOE‐ε4 carriers have superior recall on the ‘What was where?’ visual short‐term memory binding test at age 70, despite a detrimental effect of β‐amyloid
Vascular risk factors and amyloid pathology: Additive or interactive associations?
Comparison of static and dynamic analysis techniques for longitudinal analysis of amyloid PET
Associations between blood pressure across adulthood and late-life brain structure and pathology in the neuroscience substudy of the 1946 British birth cohort (Insight 46): an epidemiological study
Liver Function and Risk of Type 2 Diabetes: Bidirectional Mendelian Randomization Study