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John D. Phillips

New York Consortium in Evolutionary Primatology · US
Area of research
Molecular Biology · Pediatrics, Perinatology and Child Health
Research interest
Research interests include Porphyrin Metabolism and Disorders, Heme Oxygenase-1 and Carbon Monoxide, Neonatal Health and Biochemistry, and Folate and B Vitamins Research.
h-index
49
citations
9,467
works
259
NIH funding
primary concept
Medicine
email

Recent publications

A Prospective, Blinded Study of Symptom Prevalence and Specificity of Porphyrin Precursors in Carriers of Acute Hepatic Porphyria.
2025cited by 0position: contributordoi
The clinical management of porphyria cutanea tarda: An update
Liver International 2024cited by 12position: lastdoi
The clinical management of porphyria cutanea tarda: An update.
2024cited by 6position: contributordoi
Exploiting Differences in Heme Biosynthesis between Bacterial Species to Screen for Novel Antimicrobials
Biomolecules 2023cited by 12position: lastdoi
Loss of the mitochondrial protein Abcb10 results in altered arginine metabolism in MEL and K562 cells and nutrient stress signaling through ATF4
Journal of Biological Chemistry 2023cited by 11position: middledoi
Cimetidine Does Not Inhibit 5-Aminolevulinic Acid Synthase or Heme Oxygenase Activity: Implications for Treatment of Acute Intermittent Porphyria and Erythropoietic Protoporphyria
Biomolecules 2023cited by 10position: lastdoi
Hyperhomocysteinemia in acute hepatic porphyria (AHP) and implications for treatment with givosiran
Expert Review of Gastroenterology & Hepatology 2022cited by 26position: middledoi
MRP5 and MRP9 play a concerted role in male reproduction and mitochondrial function
Proceedings of the National Academy of Sciences 2022cited by 25position: middledoi
Acellular human amniotic fluid protects the ischemic-reperfused rat myocardium
American Journal of Physiology-Heart and Circulatory Physiology 2022cited by 10position: middledoi
Acellular human amniotic fluid protects the ischemic-reperfused rat myocardium.
2022cited by 5position: contributordoi
ABCB6 polymorphisms are not overly represented in patients with porphyria.
2022cited by 2position: contributordoi
The ubiquitous mitochondrial protein unfoldase CLPX regulates erythroid heme synthesis by control of iron utilization and heme synthesis enzyme activation and turnover
Journal of Biological Chemistry 2021cited by 31position: middledoi
The immunometabolite itaconate inhibits heme synthesis and remodels cellular metabolism in erythroid precursors
Blood Advances 2021cited by 26position: middledoi
The immunometabolite itaconate inhibits heme synthesis and remodels cellular metabolism in erythroid precursors.
2021cited by 24position: contributordoi
MRP5 and MRP9 Play a Concerted Role in Male Reproduction and Mitochondrial Function
2021cited by 0position: contributordoi
Phase 3 Trial of RNAi Therapeutic Givosiran for Acute Intermittent Porphyria
New England Journal of Medicine 2020cited by 587position: middledoi
Genome-wide CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1
Nature Immunology 2020cited by 260position: middledoi
The mitochondrial metal transporters mitoferrin1 and mitoferrin2 are required for liver regeneration and cell proliferation in mice
Journal of Biological Chemistry 2020cited by 59position: middledoi
Hepatocellular Carcinoma in Acute Hepatic Porphyrias: Results from the Longitudinal Study of the U.S. Porphyrias Consortium
Hepatology 2020cited by 49position: middledoi
Phase 1 Trial of an RNA Interference Therapy for Acute Intermittent Porphyria
New England Journal of Medicine 2019cited by 254position: middledoi
Heme biosynthesis and the porphyrias
Molecular Genetics and Metabolism 2019cited by 213position: firstdoi
EXPLORE: A Prospective, Multinational, Natural History Study of Patients with Acute Hepatic Porphyria with Recurrent Attacks
Hepatology 2019cited by 169position: middledoi
Hemozoin produced by mammals confers heme tolerance
eLife 2019cited by 51position: middledoi
Homozygous hydroxymethylbilane synthase knock-in mice provide pathogenic insights into the severe neurological impairments present in human homozygous dominant acute intermittent porphyria
Human Molecular Genetics 2019cited by 29position: middledoi
Evaluating quality of life tools in North American patients with erythropoietic protoporphyria and X‐linked protoporphyria
JIMD Reports 2019cited by 26position: middledoi
Feasibility of cellular bioenergetics as a biomarker in porphyria patients
Molecular Genetics and Metabolism Reports 2019cited by 21position: middledoi
Evaluating the Patient-Reported Outcomes Measurement Information System scales in acute intermittent porphyria
Genetics in Medicine 2019cited by 12position: middledoi
Glutamine via α-ketoglutarate dehydrogenase provides succinyl-CoA for heme synthesis during erythropoiesis
Blood 2018cited by 81position: middledoi
FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity
Journal of Biological Chemistry 2018cited by 45position: middledoi
Cirrhosis in Hemochromatosis: Independent Risk Factors in 368 HFE p.C282Y Homozygotes
Annals of Hepatology 2018cited by 38position: middledoi

Grants

NSF CISE Research Expansion Principal Investigators Conference, 2023-2024
NSF2335241$41,1452023–2025PIRePORTER
EAGER: Magnetic Field Effects on Head Direction and Subicular Place Cell Responses
NSF1349370$160,3482013–2016PIRePORTER
EAGER: Integration of magnetic and visual cues by C57BL/6 mice in a 4-armed ('plus') water maze
NSF1349515$160,0002013–2015PIRePORTER
WORKSHOP: Biomimicry - Educating a New Generation of Leaders in Sustainability - San Diego Zoo, October 2, 2009
NSF0936971$25,0002009–2010PIRePORTER
Light-dependent magnetoreception: molecular/biophysical basis
NSF0748175$315,6322008–2012PIRePORTER
Characterizing the Mechanism of Magnetoreception in C57BL/6 Mice
NSF0647188$459,5572007–2012PIRePORTER
SGER: Characterization of the Magnetic Compass in C57 BL/6 Mice
NSF0425712$118,4582004–2006PIRePORTER
Geomagnetic Position Fixing
NSF0216957$401,6872002–2006PIRePORTER
Geomagnetic Position Fixing
NSF9808420$195,0001998–2001PIRePORTER
Mechanisms of Magnetoreception
NSF9724083$99,9931997–1999PIRePORTER
Geomagnetic Position Fixing
NSF9507826$220,9991995–1999PIRePORTER
"Engineering Clinic Issues" Symposium
NSF9453953$24,4001994–1995PIRePORTER
Mechanisms of Magnetoreception
NSF9212102$262,0061992–1996PIRePORTER
CRB: Conservation Strategies for the Rapid Recovery of Depleted Populations of Large Lizards
NSF9208878$125,7981992–1995PIRePORTER
Chromatographic Signals and Modulation
NSF9024923$162,9001991–1994PIRePORTER
Fourier Transform Infrared Spectrometer for the Organic and Advanced Laboratory Curriculum
NSF9151991$16,0781991–1993PIRePORTER
CRB: Practical Assessment of Reproductive Biology of an Endangered or Threatened Species
NSF9000100$49,2191990–1992PIRePORTER
Ontogeny of Hormone-Behavior Interactions
NSF8909207$45,8471989–1992PIRePORTER
Magnetoreception and Magnetotactic Orientation
NSF8706866$173,6721988–1991PIRePORTER
Analysis of Spectra of Molecules of Astrophysical Interest
NSF8615801$210,5001987–1990PIRePORTER
Special Foreign Currency Travel Award (In Indian Currency) For Participation in the U.S.-India Exchange of Scientists Program
NSF8211685$2,6001983–1984PIRePORTER
Improved Instruction in Chemical Instrumentation
NSF8160674$16,2751981–1984PIRePORTER
Analysis of Molecular Spectra
NSF7921321$223,0001980–1983PIRePORTER
Improved Instruction in Instrumental Analytical Chemistry Laboratory
NSF8012756$9,9001980–1983PIRePORTER

Frequent collaborators

Robert J. Desnick · New York Consortium in Evolutionary Primatology13 papers (2013–2023)Manisha Balwani · University of Miami11 papers (2013–2025)Karl E. Anderson · Moderna Therapeutics (United States)10 papers (2013–2020)Herbert L. Bonkovsky · New York Consortium in Evolutionary Primatology9 papers (2013–2020)D. Montgomery Bissell · New York Consortium in Evolutionary Primatology9 papers (2013–2020)Hector A. Bergonia · University of Utah9 papers (2015–2023)Joseph R. Bloomer · University of Alabama at Birmingham7 papers (2013–2019)Harry A. Dailey · University of Georgia7 papers (2013–2023)Hetanshi Naik · Stanford Medicine7 papers (2014–2020)Bruce Wang · UCSF Helen Diller Family Comprehensive Cancer Center7 papers (2015–2025)Barry H. Paw · Brigham and Women's Hospital6 papers (2012–2020) · 6 papers (2021–2025)Makiko Yasuda · The University of Texas Medical Branch at Galveston5 papers (2013–2023)Jerry Kaplan · University of Utah5 papers (2017–2020)Martin D. Kafina · New York Medical College5 papers (2017–2018)Ashwani K. Singal · University of Louisville5 papers (2015–2020)Laurie K. Jackson · Agricultural Research Service5 papers (2016–2023)Yvette Y. Yien · UPMC Hillman Cancer Center5 papers (2017–2021)Diane M. Ward · University of Utah5 papers (2017–2023)Lin Gan · University of Rochester Medical Center4 papers (2014–2023)