Area of research
Cancer Research · Pulmonary and Respiratory Medicine
Research interest
Research interests include Cancer Genomics and Diagnostics, Prostate Cancer Treatment and Research, Sarcoma Diagnosis and Treatment, and Epigenetics and DNA Methylation.
Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks
Chromatin as an old and new anticancer target
MLL oncoprotein levels influence leukemia lineage identities
Nucleosome Patterns in Circulating Tumor DNA Reveal Transcriptional Regulation of Advanced Prostate Cancer Phenotypes
CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target
dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region
Single-cell CUT&Tag analysis of chromatin modifications in differentiation and tumor progression
Automated CUT&Tag profiling of chromatin heterogeneity in mixed-lineage leukemia
Short H2A histone variants are expressed in cancer
MYCN amplification and ATRX mutations are incompatible in neuroblastoma
Optimal therapeutic targeting by HDAC inhibition in biopsy-derived treatment-naïve diffuse midline glioma models
Histone deposition pathways determine the chromatin landscapes of H3.1 and H3.3 K27M oncohistones
Chromatin Bottlenecks in Cancer
Bringing Oncohistones into the Fold
Automated in situ chromatin profiling efficiently resolves cell types and gene regulatory programs