Area of research
Genetics · Molecular Biology
Research interest
Research interests include Medicine, Biology, Internal medicine, Kidney disease, Cell biology, and Autosomal dominant polycystic kidney disease.
Targeting GLP-1 Signaling Ameliorates Cystogenesis in a Zebrafish Model of Nephronophthisis
Cyclin-dependent kinase 4 drives cystic kidney disease in the absence of mTORC1 signaling activity
Association of mineral and bone biomarkers with adverse cardiovascular outcomes and mortality in the German Chronic Kidney Disease (GCKD) cohort
Differential Prognostic Utility of Adiposity Measures in Chronic Kidney Disease
MARVEL domain containing CMTM4 affects CXCR4 trafficking
Urine Metabolite Levels, Adverse Kidney Outcomes, and Mortality in CKD Patients: A Metabolome-wide Association Study
A molecular mechanism explaining albuminuria in kidney disease
Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans
Growth characteristics and therapeutic decision markers in von Hippel-Lindau disease patients with renal cell carcinoma
Cilia‐localized <scp>LKB</scp> 1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney
A model to predict disease progression in patients with autosomal dominant polycystic kidney disease (ADPKD): the ADPKD Outcomes Model
CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury
FAT1 mutations cause a glomerulotubular nephropathy
A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes
Genetic risk variants for membranous nephropathy: extension of and association with other chronic kidney disease aetiologies
The Future of Polycystic Kidney Disease Research—As Seen By the 12 Kaplan Awardees
FP064ASSESSING THE LONG TERM OUTCOMES OF AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD) USING THE ADPKD OUTCOMES MODEL: A UK CASE STUDY
Renal replacement therapy for autosomal dominant polycystic kidney disease (ADPKD) in Europe: prevalence and survival--an analysis of data from the ERA-EDTA Registry
Prevalence and correlates of gout in a large cohort of patients with chronic kidney disease: the German Chronic Kidney Disease (GCKD) study
mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress
RENAL DEVELOPMENT AND CYSTIC DISEASES
Development Of A Model To Predict Disease Progression In Autosomal Dominant Polycystic Kidney Disease (ADPKD)
ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3
aPKCλ/ι and aPKCζ Contribute to Podocyte Differentiation and Glomerular Maturation
Exome Capture Reveals ZNF423 and CEP164 Mutations, Linking Renal Ciliopathies to DNA Damage Response Signaling
Vertebrate kidney tubules elongate using a planar cell polarity–dependent, rosette-based mechanism of convergent extension