Dryden R. Baumfalk

Area of research

Cardiology and Cardiovascular Medicine · Complementary and alternative medicine

Research interest

Research topics from publications: Prostate cancer cell growth characteristics in serum and prostate-conditioned media from moderate-intensity exercise-trained healthy and tumor-bearing rats; Prolonged mechanical ventilation increases diaphragm arteriole circumferential stretch without changes in stress/stretch: Implications for the pathogenesis of ventilator‐induced diaphragm dysfunction; Head‐up tilt does not enhance prostate tumor perfusion or oxygenation in young rats; Effect of Hypoxia on Prostate Cancer Cell Viability in Serum and Prostate Conditioned Media from Mixed‐Intensity Exercise Trained Rats. Representative work: ) conditions. Under normoxic condition, there was a decreased AT-1 cell viability in SSM and PCM from the exercise-trained (ET) immune-competent rats, but no difference in PC-3 cell viability in SSM and PCM from ET Nude rats versus the sedentary (SED) group, or in SSM-TB from ET-TB Nude rats versus the SED-TB group. However, there was a decreased PC-3 cell viability in the PCM-TB of the ET-TB group versus SED-TB group. PC-3 cell viability in all conditioned media types was not altered between groups with hypoxia. In the prostate, exercise training did not alter 5αR2 expression levels, but increased caspase-3 expression levels. In conclusion, prior exercise status reduced prostate cancer cell Abstract Introduction Prolonged mechanical ventilation (MV; ≥6 h) results in large, time‐dependent reductions in diaphragmatic blood flow and shear stress. We tested the hypothesis that MV would impair the structural and material properties (ie, increased stress/stretch relation and/or circumferential stretch) of first‐order arterioles (1A) from the medial costal diaphragm. Methods Shear stress was estimated from isolated arterioles and prior blood flow data from the diaphragm during spontaneous breathing (SB) and prolonged MV (6 h MV). Thereafter, female Sprague‐Dawley rats (~5 months) were randomly divided into two groups, SB ( n = 6) and 6 h MV ( n = 6). Following SB and 6 h MV, 1A medial

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