Area of research
Molecular Biology · Genetics
Research interest
Research interests include Wnt/β-catenin signaling in development and cancer, Cancer-related gene regulation, Developmental Biology and Gene Regulation, and Epigenetics and DNA Methylation.
Acupuncture does not work and has no place in science-based medicine.
Deletion of an enhancer that controls Wnt gene expression following tissue injury produces increased adipogenesis in regenerated muscle
Vascularization of neonatal liver lobules presages adult liver size.
Deletion of an enhancer that controls Wnt gene expression following tissue injury produces increased adipogenesis in regenerated muscle.
A regulatory region that controls Wnt gene expression following tissue injury is required for proper muscle regeneration
A developmental biliary lineage program cooperates with Wnt activation to promote cell proliferation in hepatoblastoma
A developmental biliary lineage program cooperates with Wnt activation to promote cell proliferation in hepatoblastoma.
A primer on the pleiotropic endocrine fibroblast growth factor FGF19/FGF15
Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver.
The Lasker-Koshland Special Achievement Award in Medical Science awarded to Piet Borst.
Cholangiocytic differentiation drives cell proliferation in hepatoblastoma through Wnt-dependent FGF19 signaling
The Wnt Pathway: From Signaling Mechanisms to Synthetic Modulators
Molecular hallmarks of heterochronic parabiosis at single-cell resolution
Wnt signaling regulates hepatocyte cell division by a transcriptional repressor cascade.
Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver
3D Culture of Primary Patient-Derived Hepatoblastoma Tumoroids
Assessment of Hepatocyte Ploidy by Flow Cytometry
Author response: Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver
WNT signaling in pre-granulosa cells is required for ovarian folliculogenesis and female fertility
Pituitary stem cells produce paracrine WNT signals to control the expansion of their descendant progenitor cells
Intermittent fasting induces rapid hepatocyte proliferation to restore the hepatostat in the mouse liver
A single-cell transcriptomic atlas characterizes ageing tissues in the mouse
Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo.
<i>β</i>
-catenin-Mediated Wnt Signal Transduction Proceeds Through an Endocytosis-Independent Mechanism
Self-activation of Wnt signaling in pre-granulosa cells is required for ovarian folliculogenesis
Tissue Repair in the Mouse Liver Following Acute Carbon Tetrachloride Depends on Injury‐Induced Wnt/β‐Catenin Signaling
Perspectives on the role of Wnt biology in cancer
Perspectives on the role of Wnt biology in cancer.
Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture
Wnt signalling: conquering complexity