Area of research
Nephrology · Molecular Biology
Research interest
Research interests include Medicine, Cancer research, Internal medicine, Endocrinology, Kidney, and HDAC4.
Epigenetics in autosomal dominant polycystic kidney disease
Irisin deficiency exacerbates diet-induced insulin resistance and cardiac dysfunction in type II diabetes in mice
Critical Functions of Histone Deacetylases (HDACs) in Modulating Inflammation Associated with Cardiovascular Diseases
Deletion of PRAK Mitigates the Mitochondria Function and Suppresses Insulin Signaling in C2C12 Myoblasts Exposed to High Glucose
Irisin counteracts high glucose and fatty acid-induced cytotoxicity by preserving the AMPK-insulin receptor signaling axis in C2C12 myoblasts
Irisin Improves Myocardial Performance and Attenuates Insulin Resistance in Spontaneous Mutation (Leprdb) Mice
Selective inhibition of class IIa histone deacetylases alleviates renal fibrosis
Targeting histone methyltransferase enhancer of zeste homolog‐2 inhibits renal epithelial‐mesenchymal transition and attenuates renal fibrosis
Targeting enhancer of zeste homolog 2 protects against acute kidney injury
Irisin promotes cardiac progenitor cell‐induced myocardial repair and functional improvement in infarcted heart
Transgenic overexpression of active HDAC4 in the heart attenuates cardiac function and exacerbates remodeling in infarcted myocardium
Sodium Butyrate Protects Against High Fat Diet-Induced Cardiac Dysfunction and Metabolic Disorders in Type II Diabetic Mice
Pharmacologic targeting ERK1/2 attenuates the development and progression of hyperuricemic nephropathy in rats
Pharmacological inhibition of Src kinase protects against acute kidney injury in a murine model of renal ischemia/reperfusion
Irisin Ameliorates Hypoxia/Reoxygenation-Induced Injury through Modulation of Histone Deacetylase 4
Exendin-4 induces myocardial protection through MKK3 and Akt-1 in infarcted hearts
Enhancer of Zeste Homolog 2 Inhibition Attenuates Renal Fibrosis by Maintaining Smad7 and Phosphatase and Tensin Homolog Expression
Src inhibition blocks renal interstitial fibroblast activation and ameliorates renal fibrosis
Blocking Sirtuin 1 and 2 Inhibits Renal Interstitial Fibroblast Activation and Attenuates Renal Interstitial Fibrosis in Obstructive Nephropathy
Stimulation of glucagon-like peptide-1 receptor through exendin-4 preserves myocardial performance and prevents cardiac remodeling in infarcted myocardium
Specific inhibition of HDAC4 in cardiac progenitor cells enhances myocardial repairs
HDAC4 Degradation Mediates HDAC Inhibition‐Induced Protective Effects Against Hypoxia/Reoxygenation Injury