← back to search

Irvin S. Y. Chen

Broad Center ·
Area of research
Virology · Genetics
Research interest
Research interests include HIV Research and Treatment, Virus-based gene therapy research, RNA Interference and Gene Delivery, and T-cell and Retrovirus Studies.
h-index
66
citations
18,743
works
229
NIH funding
primary concept
email

Recent publications

Lactate oxidase nanocapsules boost T cell immunity and efficacy of cancer immunotherapy
Science Translational Medicine 2023cited by 113position: middledoi
Efficient derivation of chimeric-antigen receptor-modified TSCM cells
Frontiers in Immunology 2022cited by 19position: middledoi
Nanoencapsulated rituximab mediates superior cellular immunity against metastatic B-cell lymphoma in a complement competent humanized mouse model
Journal for ImmunoTherapy of Cancer 2021cited by 8position: middledoi
Efficient Delivery of Nerve Growth Factors to the Central Nervous System for Neural Regeneration
Advanced Materials 2019cited by 150position: middledoi
Systemic Delivery of Monoclonal Antibodies to the Central Nervous System for Brain Tumor Therapy
Advanced Materials 2019cited by 147position: middledoi
A Bioinspired Platform for Effective Delivery of Protein Therapeutics to the Central Nervous System
Advanced Materials 2019cited by 139position: middledoi
Sustained delivery and molecular targeting of a therapeutic monoclonal antibody to metastases in the central nervous system of mice
Nature Biomedical Engineering 2019cited by 105position: middledoi
Long-term persistence and function of hematopoietic stem cell-derived chimeric antigen receptor T cells in a nonhuman primate model of HIV/AIDS
PLoS Pathogens 2017cited by 118position: middledoi
HIV-1-Specific Chimeric Antigen Receptors Based on Broadly Neutralizing Antibodies
Journal of Virology 2016cited by 102position: middledoi
Phosphorylcholine polymer nanocapsules prolong the circulation time and reduce the immunogenicity of therapeutic proteins
Nano Research 2016cited by 89position: middledoi
HIV-specific Immunity Derived From Chimeric Antigen Receptor-engineered Stem Cells
Molecular Therapy 2015cited by 148position: middledoi
Engineering Cellular Resistance to HIV-1 Infection In Vivo Using a Dual Therapeutic Lentiviral Vector
Molecular Therapy — Nucleic Acids 2015cited by 64position: middledoi
Role of Phosphatidylserine Receptors in Enveloped Virus Infection
Journal of Virology 2014cited by 178position: lastdoi
Dynamics of HSPC Repopulation in Nonhuman Primates Revealed by a Decade-Long Clonal-Tracking Study
Cell stem cell 2014cited by 108position: lastdoi
Preclinical safety and efficacy of an anti–HIV-1 lentiviral vector containing a short hairpin RNA to CCR5 and the C46 fusion inhibitor
Molecular Therapy — Methods & Clinical Development 2014cited by 73position: middledoi
Engineering HIV-1-Resistant T-Cells from Short-Hairpin RNA-Expressing Hematopoietic Stem/Progenitor Cells in Humanized BLT Mice
PLoS ONE 2012cited by 85position: middledoi
Single siRNA Nanocapsules for Enhanced RNAi Delivery
Journal of the American Chemical Society 2012cited by 66position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Jing Wen · Nanjing University of Chinese Medicine8 papers (2012–2023)Masakazu Kamata · University of Alabama at Birmingham7 papers (2012–2022)Di Wu · State Grid Corporation of China (China)5 papers (2019–2021)Duo Xu · University of Wisconsin–Madison5 papers (2019–2023)Scott G. Kitchen · University of California, Los Angeles4 papers (2015–2017)Chaoyong Liu · Beijing Institute of Petrochemical Technology4 papers (2019–2019)Meng Qin · Sichuan University4 papers (2019–2019)Dong Sung An · Tianjin University4 papers (2012–2015)Yunfeng Lu · Nanyang Normal University4 papers (2012–2019)Yunfeng Lu · University of Macau4 papers (2016–2023)Jie Ren · Central South University4 papers (2019–2021)Jerome A. Zack · University of California, Los Angeles3 papers (2015–2017)Valerie Rezek · University of California, Los Angeles3 papers (2015–2017) · 3 papers (2012–2015)Emiko Kranz · APLA Health3 papers (2019–2022) · 3 papers (2012–2015)Xiangsheng Liu · Zhejiang Cancer Hospital2 papers (2019–2023)Bernard Levin · APLA Health2 papers (2015–2015)Otto O. Yang · UCLA Medical Center2 papers (2015–2016) · 2 papers (2014–2015)