Area of research
Infectious Diseases · Public Health, Environmental and Occupational Health
Research interest
Research interests include Mosquito-borne diseases and control, Viral Infections and Vectors, SARS-CoV-2 and COVID-19 Research, and Viral gastroenteritis research and epidemiology.
Epidemiological, clinical, and virological characterizations of Yezo virus infections, an emerging tick-borne orthonairovirus disease in Japan.
NS4B and NS5 mutations expand the temperature range permissive for the replication of dual-host affiliated insect-specific flaviviruses in mosquito cells.
In Vitro Selection and Characterization of Tecovirimat-resistant Mpox Virus.
Circulation of an emerging neurotropic tick-borne phenuivirus in brown bears and wildlife in northern Japan
Antiviral effect of cetylpyridinium chloride on SARS-CoV-2 in patients with COVID-19: An Observational Study
Integrated
<i>in vivo</i>
and transcriptomic analyses of lethal Oropouche virus infection reveal suppression of pathogenic host responses by antiviral therapy
SARS-CoV-2 uptake and inflammatory response in senescent endothelial cells are regulated by the BSG/VEGFR2 pathway.
Spatial gene expression analysis reveals pathological niches in Japanese encephalitis virus neuroinvasion.
Lipidated macrocyclic peptide S-880008 as a broad-spectrum SARS-CoV-2 fusion inhibitor
Mosquito-borne alphaviruses in Zambia: Isolation and characterization of Eilat and Sindbis viruses
Combination therapy with oral antiviral and anti-inflammatory drugs improves the efficacy of delayed treatment in a COVID-19 hamster model
A wide distribution of Beiji nairoviruses and related viruses in Ixodes ticks in Japan
Neuron-associated retroelement-derived protein Arc/Arg3.1 assists in the early stages of alphaherpesvirus infection in human neuronal cells.
African lineage 1a West Nile virus isolated from crocodiles exhibits low neuroinvasiveness in mice
S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and ameliorates COVID-19 severity in hamsters.
Ecological Niche Modeling of <i>Aedes</i> and <i>Culex</i> Mosquitoes: A Risk Map for Chikungunya and West Nile Viruses in Zambia.
Development of flavivirus subviral particles with low cross-reactivity by mutations of a distinct antigenic domain.
Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant.
A high-affinity aptamer with base-appended base-modified DNA bound to isolated authentic SARS-CoV-2 strains wild-type and B.1.617.2 (delta variant)
An unusually long Rift valley fever inter-epizootic period in Zambia: Evidence for enzootic virus circulation and risk for disease outbreak.
Discovery of S-217622, a Non-Covalent Oral SARS-CoV-2 3CL Protease Inhibitor Clinical Candidate for Treating COVID-19
Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant
Serological characterization of lineage II insect-specific flaviviruses compared with pathogenic mosquito-borne flaviviruses
SARS-CoV-2 variants with mutations at the S1/S2 cleavage site are generated in vitro during propagation in TMPRSS2-deficient cells.
SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis.
A novel nairovirus associated with acute febrile illness in Hokkaido, Japan.
TMPRSS11D and TMPRSS13 Activate the SARS-CoV-2 Spike Protein.
Serologic and molecular evidence for circulation of Crimean-Congo hemorrhagic fever virus in ticks and cattle in Zambia.
5-Hydroxymethyltubercidin exhibits potent antiviral activity against flaviviruses and coronaviruses, including SARS-CoV-2
Attenuated infection by a Pteropine orthoreovirus isolated from an Egyptian fruit bat in Zambia.