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Eric C. Lai

Kettering University · US
Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include MicroRNA in disease regulation, RNA Research and Splicing, RNA modifications and cancer, and Developmental Biology and Gene Regulation.
h-index
84
citations
32,384
works
290
NIH funding
primary concept
email

Recent publications

Aging Fly Cell Atlas identifies exhaustive aging features at cellular resolution
Science 2023cited by 121position: middledoi
Large-scale benchmarking of circRNA detection tools reveals large differences in sensitivity but not in precision
Nature Methods 2023cited by 100position: middledoi
Essential and recurrent roles for hairpin RNAs in silencing de novo sex chromosome conflict in Drosophila simulans
PLoS Biology 2023cited by 20position: lastdoi
miR-486 is essential for muscle function and suppresses a dystrophic transcriptome
Life Science Alliance 2022cited by 38position: middledoi
Diverse cell-specific patterns of alternative polyadenylation in Drosophila
Nature Communications 2022cited by 28position: lastdoi
Regulated dicing of <i>pre-mir-144</i> via reshaping of its terminal loop
Nucleic Acids Research 2022cited by 17position: lastdoi
A neural m6A/Ythdf pathway is required for learning and memory in Drosophila
Nature Communications 2021cited by 91position: lastdoi
Rapid evolutionary dynamics of an expanding family of meiotic drive factors and their hpRNA suppressors
Nature Ecology & Evolution 2021cited by 48position: lastdoi
Cancer-associated mutations in DICER1 RNase IIIa and IIIb domains exert similar effects on miRNA biogenesis
Nature Communications 2019cited by 80position: lastdoi
Transcriptional Regulation of the Glutamate/GABA/Glutamine Cycle in Adult Glia Controls Motor Activity and Seizures in <i>Drosophila</i>
Journal of Neuroscience 2019cited by 41position: middledoi
The hpRNA/RNAi Pathway Is Essential to Resolve Intragenomic Conflict in the Drosophila Male Germline
Developmental Cell 2018cited by 84position: lastdoi
Dual Strategies for Argonaute2-Mediated Biogenesis of Erythroid miRNAs Underlie Conserved Requirements for Slicing in Mammals
Molecular Cell 2018cited by 76position: lastdoi
The m6A pathway facilitates sex determination in Drosophila
Nature Communications 2017cited by 203position: lastdoi
A transgenic resource for conditional competitive inhibition of conserved Drosophila microRNAs
Nature Communications 2015cited by 91position: middledoi
Analysis of Nearly One Thousand Mammalian Mirtrons Reveals Novel Features of Dicer Substrates
PLoS Computational Biology 2015cited by 84position: lastdoi
Selective Suppression of the Splicing-Mediated MicroRNA Pathway by the Terminal Uridyltransferase Tailor
Molecular Cell 2015cited by 71position: lastdoi
Genome-wide Analysis of Drosophila Circular RNAs Reveals Their Structural and Sequence Properties and Age-Dependent Neural Accumulation
Cell Reports 2014cited by 1,075position: lastdoi
Diversity and dynamics of the Drosophila transcriptome
Nature 2014cited by 817position: middledoi
Comparative analysis of the transcriptome across distant species
Nature 2014cited by 320position: middledoi
A Genome-Wide Survey of Sexually Dimorphic Expression of <i>Drosophila</i> miRNAs Identifies the Steroid Hormone-Induced miRNA let-7 as a Regulator of Sexual Identity
Genetics 2014cited by 77position: middledoi
Adaptive Regulation of Testis Gene Expression and Control of Male Fertility by the Drosophila Hairpin RNA Pathway
Molecular Cell 2014cited by 59position: lastdoi
A genome-wide transgenic resource for conditional expression of<i>Drosophila</i>microRNAs
Development 2012cited by 93position: lastdoi
Functional parameters of Dicer-independent microRNA biogenesis
RNA 2012cited by 90position: lastdoi
RNase III-independent microRNA biogenesis in mammalian cells
RNA 2012cited by 40position: lastdoi

Grants

Pulsed Field DNA Sequencing
NSF9016214$184,0621991–1995PIRePORTER

Frequent collaborators

Jeffrey Vedanayagam · University of Rochester6 papers (2017–2023)Jiayu Wen · Jinan University5 papers (2014–2018)Ching‐Jung Lin · University of California, Davis5 papers (2015–2023) · 4 papers (2012–2015)Jr-Shiuan Yang · Cornell University4 papers (2012–2018)Brian Joseph · Massachusetts Institute of Technology3 papers (2014–2021)David Jee · Memorial Sloan Kettering Cancer Center3 papers (2015–2022) · 3 papers (2012–2015)Yen‐Chung Chen · New York University2 papers (2022–2023)Lijuan Kan · Virginia Tech2 papers (2017–2021)David Van Vactor · Harvard University2 papers (2012–2015)Norbert Perrimon · Harvard University2 papers (2012–2015)Fuqu Hu · Texas A&M University2 papers (2015–2018)Raphaëlle Dubruille · Université Claude Bernard Lyon 12 papers (2018–2023)Tudor A. Fulga · Tufts University2 papers (2012–2015) · 2 papers (2022–2023)Sol Shenker · Q Therapeutics (United States)2 papers (2014–2015)Hong Duan · Xihua University2 papers (2012–2014)Katsutomo Okamura · National University of Singapore2 papers (2014–2015) · 2 papers (2012–2012)