Area of research
Molecular Biology · Aging
Research interest
Research interests include Genetics, Aging, and Longevity in Model Organisms, RNA Research and Splicing, CRISPR and Genetic Engineering, and RNA modifications and cancer.
Specialized germline P-bodies are required to specify germ cell fate in <i>Caenorhabditis elegans</i> embryos
Improving the specificity of nucleic acid detection with endonuclease-actuated degradation
Intrinsically disordered regions: a platform for regulated assembly of biomolecular condensates
Regulation of biomolecular condensates by interfacial protein clusters
Recruitment of mRNAs to P granules by condensation with intrinsically-disordered proteins
Puromycin reactivity does not accurately localize translation at the subcellular level
Cell-free reconstitution of multi-condensate assemblies
Author Correction: A gel phase promotes condensation of liquid P granules in Caenorhabditis elegans embryos
A gel phase promotes condensation of liquid P granules in Caenorhabditis elegans embryos
P Granules Protect RNA Interference Genes from Silencing by piRNAs
Rapid Tagging of Human Proteins with Fluorescent Reporters by Genome Engineering using Double‐Stranded DNA Donors
The P Granules of C. elegans: A Genetic Model for the Study of RNA–Protein Condensates
Single-molecule study reveals the frenetic lives of proteins in gradients
Precision genome editing using CRISPR-Cas9 and linear repair templates in C. elegans
Precision genome editing using synthesis-dependent repair of Cas9-induced DNA breaks
Nanos promotes epigenetic reprograming of the germline by down-regulation of the THAP transcription factor LIN-15B
MIP-MAP: High-Throughput Mapping of <i>Caenorhabditis elegans</i> Temperature-Sensitive Mutants via Molecular Inversion Probes
Spatial patterning of P granules by RNA-induced phase separation of the intrinsically-disordered protein MEG-3
Loss-of-function genetic tools for animal models: cross-species and cross-platform differences
High Efficiency, Homology-Directed Genome Editing in <i>Caenorhabditis elegans</i> Using CRISPR-Cas9 Ribonucleoprotein Complexes
Lattice light-sheet microscopy: Imaging molecules to embryos at high spatiotemporal resolution
Regulation of RNA granule dynamics by phosphorylation of serine-rich, intrinsically disordered proteins in C. elegans
Scalable and Versatile Genome Editing Using Linear DNAs with Microhomology to Cas9 Sites in<i>Caenorhabditis elegans</i>
The PAR network: redundancy and robustness in a symmetry-breaking system
The P granule component PGL-1 promotes the localization and silencing activity of the PUF protein FBF-2 in germline stem cells