Area of research
Infectious Diseases · Molecular Biology
Research interest
Research interests include Mycobacterium tuberculosis, Pyrazinamide, Prodrug, Biochemistry, Biology, and Mutant.
Pyrazinamide triggers degradation of its target aspartate decarboxylase
Phase variation in <i>Mycobacterium tuberculosis glpK</i> produces transiently heritable drug tolerance
Pyrazinoic Acid Inhibits Mycobacterial Coenzyme A Biosynthesis by Binding to Aspartate Decarboxylase PanD
Pyrazinamide Resistance Is Caused by Two Distinct Mechanisms: Prevention of Coenzyme A Depletion and Loss of Virulence Factor Synthesis
Host-Mediated Bioactivation of Pyrazinamide: Implications for Efficacy, Resistance, and Therapeutic Alternatives