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Alexandra Drakaki

University of Colorado Denver · US
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Area of research
Surgery · Oncology
Research interest
Research interests include Bladder and Urothelial Cancer Treatments, Cancer Immunotherapy and Biomarkers, Urinary and Genital Oncology Studies, and Renal cell carcinoma treatment.
h-index
37
citations
8,749
works
258
NIH funding
primary concept
Medicine
email

Recent publications

NCCN Guidelines® Insights: Testicular Cancer, Version 2.2025
Journal of the National Comprehensive Cancer Network 2025cited by 19position: middledoi
EV-302: Updated analysis from the phase 3 global study of enfortumab vedotin in combination with pembrolizumab (EV+P) vs chemotherapy (chemo) in previously untreated locally advanced or metastatic urothelial carcinoma (la/mUC).
Journal of Clinical Oncology 2025cited by 16position: middledoi
Datopotamab deruxtecan (Dato-DXd) in locally advanced/metastatic urothelial cancer: Updated results from the phase 1 TROPIONPanTumor01 study.
Journal of Clinical Oncology 2025cited by 13position: middledoi
A first-in-human phase 1 study of LY3866288 (LOXO-435), a potent, highly isoform-selective FGFR3 inhibitor (FGFR3i) in advanced solid tumors with <i>FGFR3</i> alterations: Initial results from FORAGER-1.
Journal of Clinical Oncology 2025cited by 13position: lastdoi
Exploratory subgroup analyses of EV-302: a phase III global study to evaluate enfortumab vedotin in combination with pembrolizumab versus chemotherapy in previously untreated locally advanced or metastatic urothelial carcinoma
ESMO Open 2025cited by 8position: middledoi
Casdatifan (Cas) monotherapy in patients (pts) with previously treated clear cell renal cell carcinoma (ccRCC): Safety, efficacy and subgroup analysis across multiple doses from ARC-20, a phase 1 open-label study.
Journal of Clinical Oncology 2025cited by 5position: middledoi
Combination casdatifan plus cabozantinib expansion cohort of phase 1 ARC-20 study in previously treated patients with clear cell renal cell carcinoma.
Journal of Clinical Oncology 2025cited by 3position: lastdoi
Enfortumab Vedotin and Pembrolizumab in Untreated Advanced Urothelial Cancer
New England Journal of Medicine 2024cited by 861position: middledoi
Significance of TP53, CDKN2A, SMAD4 and KRAS in Pancreatic Cancer
Current Issues in Molecular Biology 2024cited by 77position: middledoi
Atezolizumab monotherapy for metastatic urothelial carcinoma: final analysis from the phase II IMvigor210 trial
ESMO Open 2024cited by 26position: middledoi
Safety and Activity of Immune Checkpoint Inhibitors in People Living With HIV and Cancer: A Real-World Report From the Cancer Therapy Using Checkpoint Inhibitors in People Living With HIV-International (CATCH-IT) Consortium
Journal of Clinical Oncology 2023cited by 65position: middledoi
The Potential Revolution of Cancer Treatment with CRISPR Technology
Cancers 2023cited by 62position: lastdoi
Safety and efficacy of immune checkpoint inhibitors in advanced penile cancer: report from the Global Society of Rare Genitourinary Tumors
JNCI Journal of the National Cancer Institute 2023cited by 54position: middledoi
Clonally expanded, thyrotoxic effector CD8 <sup>+</sup> T cells driven by IL-21 contribute to checkpoint inhibitor thyroiditis
Science Translational Medicine 2023cited by 37position: middledoi
Prognostic Value of End-of-Treatment PSMA PET/CT in Patients Treated with<sup>177</sup>Lu-PSMA Radioligand Therapy: A Retrospective, Single-Center Analysis
Journal of Nuclear Medicine 2023cited by 20position: middledoi
Inhibition of IL-17A Protects against Thyroid Immune-Related Adverse Events while Preserving Checkpoint Inhibitor Antitumor Efficacy
The Journal of Immunology 2022cited by 45position: middledoi
A phase 3, randomized, open-label, multicenter, global study of the efficacy and safety of durvalumab (D) + tremelimumab (T) + enfortumab vedotin (EV) or D + EV for neoadjuvant treatment in cisplatin-ineligible muscle-invasive bladder cancer (MIBC) (VOLGA).
Journal of Clinical Oncology 2022cited by 38position: middledoi
Association Between Sites of Metastasis and Outcomes With Immune Checkpoint Inhibitors in Advanced Urothelial Carcinoma
Clinical Genitourinary Cancer 2022cited by 27position: middledoi
Treatment Rechallenge With Immune Checkpoint Inhibitors in Advanced Urothelial Carcinoma
Clinical Genitourinary Cancer 2022cited by 23position: middledoi
Adjuvant atezolizumab versus observation in muscle-invasive urothelial carcinoma (IMvigor010): a multicentre, open-label, randomised, phase 3 trial
The Lancet Oncology 2021cited by 409position: middledoi
A New Prognostic Model in Patients with Advanced Urothelial Carcinoma Treated with First-line Immune Checkpoint Inhibitors
European Urology Oncology 2021cited by 62position: middledoi
Safety and efficacy of nivolumab plus ipilimumab in patients with advanced renal cell carcinoma with brain metastases: CheckMate 920
Cancer 2021cited by 49position: middledoi
Clinical Outcomes of Platinum-ineligible Patients with Advanced Urothelial Carcinoma Treated With First-line PD1/L1 Inhibitors
Clinical Genitourinary Cancer 2021cited by 38position: middledoi
Immune checkpoint inhibitors in advanced upper and lower tract urothelial carcinoma: a comparison of outcomes
British Journal of Urology 2021cited by 28position: middledoi
Association of prior local therapy and outcomes with programmed‐death ligand‐1 inhibitors in advanced urothelial cancer
British Journal of Urology 2021cited by 5position: middledoi
Association of baseline systemic corticosteroid use with overall survival and time to next treatment in patients receiving immune checkpoint inhibitor therapy in real-world US oncology practice for advanced non-small cell lung cancer, melanoma, or urothelial carcinoma
OncoImmunology 2020cited by 63position: firstdoi
Histological Subtypes and Response to PD-1/PD-L1 Blockade in Advanced Urothelial Cancer: A Retrospective Study
The Journal of Urology 2020cited by 61position: middledoi
“Real-world” outcomes and prognostic indicators among patients with high-risk muscle-invasive urothelial carcinoma
Urologic Oncology Seminars and Original Investigations 2020cited by 24position: firstdoi
Pegilodecakin combined with pembrolizumab or nivolumab for patients with advanced solid tumours (IVY): a multicentre, multicohort, open-label, phase 1b trial
The Lancet Oncology 2019cited by 119position: middledoi
Impact of performance status on treatment outcomes: A real‐world study of advanced urothelial cancer treated with immune checkpoint inhibitors
Cancer 2019cited by 89position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Pedro C. Barata · Southwestern Medical Center6 papers (2018–2025)Allan J. Pantuck · Urologic Research Institute6 papers (2016–2023)Karim Chamie · UCLA Medical Center5 papers (2016–2020)Petros Grivas · Second Foundation (United States)5 papers (2018–2022)Guru Sonpavde · AdventHealth Orlando3 papers (2018–2021)Nicholas M. Donin · University of California, Los Angeles3 papers (2016–2017)Bradley A. McGregor · Harvard University3 papers (2019–2025)Jae‐Lyun Lee · Ulsan College3 papers (2021–2025)Gopa Iyer · New York Oncology Hematology3 papers (2024–2025)Seema Rao Gorla · Astellas Pharma (United States)3 papers (2024–2025)Jens Bedke · Medical University of Vienna3 papers (2024–2025)Blanca Homet Moreno · Merck & Co., Inc., Rahway, NJ, USA (United States)3 papers (2024–2025)Thomas Powles · St Bartholomew's Hospital3 papers (2022–2025)Xuesong Yu · State Grid Corporation of China (China)3 papers (2024–2025)Arie S. Belldegrun · University of California, Los Angeles3 papers (2016–2018)Ashok Gupta · Delhi Technological University3 papers (2016–2022)Eiji Kikuchi · St. Marianna University School of Medicine3 papers (2024–2025)Christof Vulsteke · The European Academy of Gynaecological Surgery3 papers (2024–2025)Shilpa Gupta · Vels University3 papers (2022–2025)Peter H. O’Donnell · University of Illinois Chicago3 papers (2016–2024)
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