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J. Robert Dorkin

Massachusetts Institute of Technology · US
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Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include In vivo, Biology, Gene silencing, Messenger RNA, Nucleic acid, and Genetic enhancement.
h-index
citations
8,588
works
14
NIH funding
primary concept
email

Recent publications

Cytosine base editing inhibits hepatitis B virus replication and reduces HBsAg expression in vitro and in vivo
Molecular Therapy — Nucleic Acids 2023cited by 33position: middledoi
Synthesis and Biological Evaluation of Ionizable Lipid Materials for the In Vivo Delivery of Messenger RNA to B Lymphocytes
Advanced Materials 2017cited by 278position: middledoi
Rapid, Single-Cell Analysis and Discovery of Vectored mRNA Transfection In Vivo with a loxP-Flanked tdTomato Reporter Mouse
Molecular Therapy — Nucleic Acids 2017cited by 100position: middledoi
Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo
Nature Biotechnology 2016cited by 867position: middledoi
Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy
Nano Letters 2016cited by 693position: middledoi
Bioinspired Alkenyl Amino Alcohol Ionizable Lipid Materials for Highly Potent In Vivo mRNA Delivery
Advanced Materials 2016cited by 241position: middledoi
Therapeutic efficacy in a hemophilia B model using a biosynthetic mRNA liver depot system
Gene Therapy 2016cited by 156position: middledoi
Poly(glycoamidoamine) Brushes Formulated Nanomaterials for Systemic siRNA and mRNA Delivery in Vivo
Nano Letters 2016cited by 110position: middledoi
Non-viral vectors for gene-based therapy
Nature Reviews Genetics 2014cited by 3,060position: middledoi
Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity
Nature Communications 2014cited by 615position: middledoi
Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates
Proceedings of the National Academy of Sciences 2014cited by 477position: middledoi
Lipid‐Like Nanomaterials for Simultaneous Gene Expression and Silencing In Vivo
Advanced Healthcare Materials 2014cited by 61position: middledoi
Delivery materials for siRNA therapeutics
Nature Materials 2013cited by 1,770position: middledoi
<i>In Vitro</i>–<i>In Vivo</i> Translation of Lipid Nanoparticles for Hepatocellular siRNA Delivery
ACS Nano 2012cited by 127position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Daniel G. Anderson · Massachusetts Institute of Technology12 papers (2012–2017)Róbert Langer · Laboratoire d’immunologie intégrative du cancer8 papers (2014–2017) · 4 papers (2016–2017)Owen S. Fenton · Massachusetts Institute of Technology4 papers (2014–2017)Kevin Kauffman · Massachusetts Institute of Technology4 papers (2016–2017) · 4 papers (2016–2017)Matthias A. Oberli · Massachusetts Institute of Technology3 papers (2016–2017)Hao Yin · Massachusetts Institute of Technology3 papers (2014–2016)Arturo J. Vegas · Massachusetts Institute of Technology3 papers (2013–2014)Philip Chang · Massachusetts Institute of Technology3 papers (2012–2016)Yizhou Dong · Allen Institute for Brain Science3 papers (2014–2016)Benjamin C. Tang · Harvard University2 papers (2014–2016)Rebecca L. McClellan · Massachusetts Institute of Technology2 papers (2016–2017)Junghoon Yang · Massachusetts Institute of Technology2 papers (2016–2016)Ana Jaklenec · Massachusetts Institute of Technology2 papers (2016–2017)Rosemary Kanasty · Massachusetts Institute of Technology2 papers (2013–2014)Mark W. Tibbitt · ETH Zurich2 papers (2016–2017)Ahmed A. Eltoukhy · Massachusetts Institute of Technology2 papers (2014–2014)Kathryn A. Whitehead · Massachusetts Institute of Technology2 papers (2012–2014)J. Matthews · University of Chicago2 papers (2012–2014)
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