Area of research
Molecular Biology · Neurology
Research interest
Research interests include Neuroscience and Neuropharmacology Research, Ion Transport and Channel Regulation, Neuroinflammation and Neurodegeneration Mechanisms, and Ion channel regulation and function.
Genome-wide enhancer-gene regulatory maps of liver reveal novel regulatory mechanisms underlying NAFLD pathogenesis
Single-Cell Analysis in Cerebrovascular Research: Primed for Breakthroughs and Clinical Impact
WNK kinases sense molecular crowding and rescue cell volume via phase separation
Inhibition of Na <sup>+</sup> /H <sup>+</sup> exchanger modulates microglial activation and scar formation following microelectrode implantation
New Mechanistic Insights, Novel Treatment Paradigms, and Clinical Progress in Cerebrovascular Diseases
Targeted disruption of Kv2.1-VAPA association provides neuroprotection against ischemic stroke in mice by declustering Kv2.1 channels
WNK-SPAK/OSR1-CCC signaling in ischemic brain damage
A Novel Na <sup>+</sup> -K <sup>+</sup> -Cl <sup>−</sup> Cotransporter 1 Inhibitor STS66* Reduces Brain Damage in Mice After Ischemic Stroke
Blockade of Na/H exchanger stimulates glioma tumor immunogenicity and enhances combinatorial TMZ and anti-PD-1 therapy
Ischemic Injury-Induced CaMKIIδ and CaMKIIγ Confer Neuroprotection Through the NF-κB Signaling Pathway
Inhibition of Na + -K + -2Cl − cotransporter attenuates blood-brain-barrier disruption in a mouse model of traumatic brain injury
Targeting a Potassium Channel/Syntaxin Interaction Ameliorates Cell Death in Ischemic Stroke
<scp>TGF</scp>β‐<scp>TAZ</scp>/<scp>SRF</scp> signalling regulates vascular smooth muscle cell differentiation
Emerging roles of Na+/H+ exchangers in epilepsy and developmental brain disorders
Peripheral motor neuropathy is associated with defective kinase regulation of the KCC3 cotransporter
Functional kinomics establishes a critical node of volume-sensitive cation-Cl− cotransporter regulation in the mammalian brain
Deletion of the WNK3-SPAK kinase complex in mice improves radiographic and clinical outcomes in malignant cerebral edema after ischemic stroke
Ion Transporters in Brain Tumors
Na+/H+ exchanger in the regulation of platelet activation and paradoxical effects of cariporide
GABA receptors in brain development, function, and injury
Upregulation of NHE1 protein expression enables glioblastoma cells to escape TMZ-mediated toxicity via increased H<sup>+</sup>extrusion, cell migration and survival
P718A novel TGF beta-dependent signalling pathway regulating vascular smooth muscle cell differentiation
Intracellular pH reduction prevents excitotoxic and ischemic neuronal death by inhibiting NADPH oxidase
TrkB Receptor Agonist 7, 8 Dihydroxyflavone Triggers Profound Gender- Dependent Neuroprotection in Mice After Perinatal Hypoxia and Ischemia