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Helen Mackay

Sunnybrook Health Science Centre · CA
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Area of research
Reproductive Medicine · Obstetrics and Gynecology
Research interest
Research interests include Ovarian cancer diagnosis and treatment, Endometrial and Cervical Cancer Treatments, Angiogenesis and VEGF in Cancer, and PARP inhibition in cancer therapy.
h-index
56
citations
13,255
works
334
NIH funding
primary concept
Medicine
email

Recent publications

Incorporation of triapine (T) to cisplatin chemoradiation (CRT) for locally advanced cervical and vaginal cancer: Results from NRG-GY006, a phase III randomized trial
Gynecologic Oncology 2025cited by 9position: middledoi
First-Line Lenvatinib Plus Pembrolizumab Versus Chemotherapy for Advanced Endometrial Cancer: A Randomized, Open-Label, Phase III Trial
Journal of Clinical Oncology 2024cited by 52position: middledoi
Cediranib and Olaparib Combination Compared With Cediranib or Olaparib Alone, or Chemotherapy in Platinum-Resistant or Primary Platinum-Refractory Ovarian Cancer: NRG-GY005
Journal of Clinical Oncology 2024cited by 22position: middledoi
Lenvatinib Plus Pembrolizumab in Previously Treated Advanced Endometrial Cancer: Updated Efficacy and Safety From the Randomized Phase III Study 309/KEYNOTE-775
Journal of Clinical Oncology 2023cited by 139position: middledoi
NRG‐GY012: Randomized phase 2 study comparing olaparib, cediranib, and the combination of cediranib/olaparib in women with recurrent, persistent, or metastatic endometrial cancer
Cancer 2023cited by 16position: lastdoi
Incorporation of triapine (T) with cisplatin chemoradiation (CRT) for locally advanced cervical and vaginal cancer: Results from NRG-GY006, a phase III randomized trial.
Journal of Clinical Oncology 2023cited by 13position: middledoi
Clinical research in ovarian cancer: consensus recommendations from the Gynecologic Cancer InterGroup
The Lancet Oncology 2022cited by 139position: middledoi
Endometrial cancer
Nature Reviews Disease Primers 2021cited by 669position: middledoi
Clinical Cancer Advances 2021: ASCO's Report on Progress Against Cancer
Journal of Clinical Oncology 2021cited by 93position: middledoi
Therapeutic Targets and Opportunities in Endometrial Cancer: Update on Endocrine Therapy and Nonimmunotherapy Targeted Options
American Society of Clinical Oncology Educational Book 2020cited by 35position: firstdoi
Enhanced breast cancer progression by mutant p53 is inhibited by the circular RNA circ-Ccnb1
Cell Death and Differentiation 2018cited by 140position: middledoi
Moving forward with actionable therapeutic targets and opportunities in endometrial cancer: NCI clinical trials planning meeting report on identifying key genes and molecular pathways for targeted endometrial cancer trials
Oncotarget 2017cited by 24position: firstdoi
HER2 Testing and Clinical Decision Making in Gastroesophageal Adenocarcinoma: Guideline From the College of American Pathologists, American Society for Clinical Pathology, and American Society of Clinical Oncology
Archives of Pathology & Laboratory Medicine 2016cited by 245position: middledoi
Endometrial cancer: Not your grandmother's cancer
Cancer 2016cited by 201position: lastdoi
<i>HER2</i>Testing and Clinical Decision Making in Gastroesophageal Adenocarcinoma
American Journal of Clinical Pathology 2016cited by 66position: middledoi
A randomized, placebo-controlled phase II trial comparing gemcitabine monotherapy to gemcitabine in combination with AZD 1775 (MK 1775) in women with recurrent, platinum-resistant epithelial ovarian, primary peritoneal, or Fallopian tube cancers: Trial of Princess Margaret, Mayo, Chicago, and California consortia.
Journal of Clinical Oncology 2015cited by 5position: middledoi
Evidence for a time-dependent association between FOLR1 expression and survival from ovarian carcinoma: implications for clinical testing. An Ovarian Tumour Tissue Analysis consortium study
British Journal of Cancer 2014cited by 105position: middledoi
State of the science in cervical cancer: Where we are today and where we need to go
Cancer 2014cited by 48position: middledoi
Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study
The Lancet Oncology 2013cited by 430position: middledoi
Vascular Endothelial Growth Factor Pathway Polymorphisms as Prognostic and Pharmacogenetic Factors in Cancer: A Systematic Review and Meta-analysis
Clinical Cancer Research 2012cited by 51position: middledoi
ENMD-2076, an oral inhibitor of angiogenic and proliferation kinases, has activity in recurrent, platinum resistant ovarian cancer
European Journal of Cancer 2012cited by 45position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Gini F. Fleming · Sydney Local Health District4 papers (2012–2020)Elise C. Kohn · National Cancer Institute3 papers (2014–2024)Charles A. Leath · St. Vincent's Birmingham3 papers (2023–2025)Jayanthi Lea · Southwestern Medical Center3 papers (2023–2025)Jyoti Mayadev · La Jolla Alcohol Research2 papers (2023–2025)Richard G. Moore · University of Rochester2 papers (2023–2024)Angela N. Bartley · Trinity Health Ann Arbor Hospital2 papers (2016–2016)Joan L. Walker · Cornell University2 papers (2023–2025)Carol Aghajanian · AstraZeneca (Italy)2 papers (2023–2025) · 2 papers (2016–2016)Jessica N. McAlpine · BC Cancer Agency2 papers (2016–2017)Megan L. Troxell · Stanford Medicine2 papers (2016–2016)Amit M. Oza · University Health Network2 papers (2012–2015)Alfredo Carrato · Universidad de Alcalá2 papers (2016–2016)Isabelle Ray‐Coquard · Université Claude Bernard Lyon 12 papers (2021–2023)Vicky Makker · University College London2 papers (2021–2023)Margaret L. Gulley · University of Vermont2 papers (2016–2016)Matthew A. Powell · NRG Oncology2 papers (2023–2024)Nofisat Ismaila · McMaster University2 papers (2016–2016)Sanjay Kakar · University of California, San Francisco2 papers (2016–2016)
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