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Rudolph E. Tanzi

Harvard University · US
Area of research
Physiology · Pharmacology
Research interest
Research interests include Alzheimer's disease research and treatments, Cholinesterase and Neurodegenerative Diseases, Bioinformatics and Genomic Networks, and Dementia and Cognitive Impairment Research.
h-index
143
citations
111,466
works
831
NIH funding
primary concept
Medicine
email

Recent publications

Modifiable risk factors for stroke, dementia and late-life depression: a systematic review and DALY-weighted risk factors for a composite outcome
Journal of Neurology Neurosurgery & Psychiatry 2025cited by 21position: middledoi
Cognitive and Alzheimer's disease biomarker effects of oral nicotinamide riboside (NR) supplementation in older adults with subjective cognitive decline and mild cognitive impairment
Alzheimer s & Dementia Translational Research & Clinical Interventions 2025cited by 8position: middledoi
Effects of nicotinamide riboside on NAD+ levels, cognition, and symptom recovery in long-COVID: a randomized controlled trial
EClinicalMedicine 2025cited by 2position: middledoi
Single-cell multiregion dissection of Alzheimer’s disease
Nature 2024cited by 253position: middledoi
Effects of intensive lifestyle changes on the progression of mild cognitive impairment or early dementia due to Alzheimer’s disease: a randomized, controlled clinical trial
Alzheimer s Research & Therapy 2024cited by 127position: middledoi
Gene therapy for CNS disorders: modalities, delivery and translational challenges
Nature reviews. Neuroscience 2024cited by 86position: middledoi
Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner
Molecular Neurodegeneration 2024cited by 54position: middledoi
Engineered 3D human neurovascular model of Alzheimer's disease to study vascular dysfunction
Biomaterials 2024cited by 34position: middledoi
A framework for translating tauopathy therapeutics: Drug discovery to clinical trials
Alzheimer s & Dementia 2024cited by 24position: middledoi
Early modulation of the gut microbiome by female sex hormones alters amyloid pathology and microglial function
Scientific Reports 2024cited by 17position: middledoi
The predictive validity of a Brain Care Score for late-life depression and a composite outcome of dementia, stroke, and late-life depression: data from the UK Biobank cohort
Frontiers in Psychiatry 2024cited by 14position: middledoi
Sensory Dysfunction, Microbial Infections, and Host Responses in Alzheimer's Disease
The Journal of Infectious Diseases 2024cited by 9position: middledoi
SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)
Nature Immunology 2023cited by 278position: middledoi
The neuroimmune axis of Alzheimer’s disease
Genome Medicine 2023cited by 273position: lastdoi
APOE4 impairs the microglial response in Alzheimer’s disease by inducing TGFβ-mediated checkpoints
Nature Immunology 2023cited by 188position: middledoi
Adult hippocampal neurogenesis in Alzheimer’s disease: A roadmap to clinical relevance
Cell stem cell 2023cited by 155position: middledoi
The predictive validity of a Brain Care Score for dementia and stroke: data from the UK Biobank cohort
Frontiers in Neurology 2023cited by 44position: middledoi
A Photolabile Curcumin‐Diazirine Analogue Enables Phototherapy with Physically and Molecularly Produced Light for Alzheimer's Disease Treatment**
Angewandte Chemie International Edition 2023cited by 40position: middledoi
Establishment of a consensus protocol to explore the brain pathobiome in patients with mild cognitive impairment and Alzheimer's disease
Alzheimer s & Dementia 2023cited by 32position: lastdoi
Accelerating the in vitro emulation of Alzheimer’s disease-associated phenotypes using a novel 3D blood-brain barrier neurosphere co-culture model
Frontiers in Bioengineering and Biotechnology 2023cited by 26position: middledoi
Development and Pharmacochemical Characterization Discover a Novel Brain-Permeable HDAC11-Selective Inhibitor with Therapeutic Potential by Regulating Neuroinflammation in Mice
Journal of Medicinal Chemistry 2023cited by 24position: middledoi
Evaluation of bumetanide as a potential therapeutic agent for Alzheimer’s disease
Frontiers in Pharmacology 2023cited by 22position: middledoi
Protective Alzheimer's disease-associated APP A673T variant predominantly decreases sAPPβ levels in cerebrospinal fluid and 2D/3D cell culture models
Neurobiology of Disease 2023cited by 22position: middledoi
Author Correction: SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)
Nature Immunology 2023cited by 7position: middledoi
Effect of sodium phenylbutyrate/taurursodiol on tracheostomy/ventilation-free survival and hospitalisation in amyotrophic lateral sclerosis: long-term results from the CENTAUR trial
Journal of Neurology Neurosurgery & Psychiatry 2022cited by 65position: middledoi
Primary prevention recommendations to reduce the risk of cognitive decline
Alzheimer s & Dementia 2022cited by 56position: lastdoi
Nutritional metabolism and cerebral bioenergetics in Alzheimer's disease and related dementias
Alzheimer s & Dementia 2022cited by 45position: middledoi
Enhanced activity of Alzheimer disease-associated variant of protein kinase Cα drives cognitive decline in a mouse model
Nature Communications 2022cited by 40position: middledoi
Neurotechnological Approaches to the Diagnosis and Treatment of Alzheimer’s Disease
Frontiers in Neuroscience 2022cited by 38position: lastdoi
Infection and inflammation: New perspectives on Alzheimer's disease
Brain Behavior & Immunity - Health 2022cited by 35position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

· 14 papers (2013–2024)Sangram S. Sisodia · University of Chicago10 papers (2013–2024) · 8 papers (2014–2023)Steven L. Wagner · University of California San Diego6 papers (2014–2021) · 5 papers (2013–2019)Enjana Bylykbashi · Virginia Commonwealth University5 papers (2015–2020)Xiaoqiong Zhang · University of Chicago5 papers (2014–2024) · 5 papers (2013–2024)Robert D. Moir · Drexel University5 papers (2015–2022)Mehdi Jorfi · University of Fribourg4 papers (2022–2024)David M. Holtzman · University of Alabama at Birmingham4 papers (2013–2024)Kristina Mullin · Harvard University4 papers (2013–2019) · 4 papers (2016–2024) · 4 papers (2015–2020)Eugene B. Chang · University of Illinois Chicago4 papers (2016–2024)Lee E. Goldstein · Boston University4 papers (2012–2022)Kevin D. Rynearson · University of California San Diego3 papers (2014–2021)Marco Colonna · BJC HealthCare3 papers (2016–2020) · 3 papers (2023–2024)Julia Michalkiewicz · Illinois College3 papers (2021–2024)