Area of research
Hematology · Molecular Biology
Research interest
Research interests include Multiple Myeloma Research and Treatments, Protein Degradation and Inhibitors, Ubiquitin and proteasome pathways, and Cancer Genomics and Diagnostics.
Early tolerance and late persistence as alternative drug responses in cancer
UNCAN.eu: Toward a European Federated Cancer Research Data Hub
Clinical bioinformatics desiderata for molecular tumor boards
Cancer Evolution: A Multifaceted Affair
Longitudinal analysis of T cell receptor repertoires reveals shared patterns of antigen-specific response to SARS-CoV-2 infection
Neutralising reactivity against SARS-CoV-2 Delta and Omicron variants by vaccination and infection history
Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation
The WNT receptor ROR2 drives the interaction of multiple myeloma cells with the microenvironment through AKT activation
Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression
Highly similar genomic landscapes in monoclonal B-cell lymphocytosis and ultra-stable chronic lymphocytic leukemia with low frequency of driver mutations
The AP-1 transcription factor JunB is essential for multiple myeloma cell proliferation and drug resistance in the bone marrow microenvironment
Pathological glycogenesis through glycogen synthase 1 and suppression of excessive AMP kinase activity in myeloid leukemia cells
Disentangling the microRNA regulatory<i>milieu</i>in multiple myeloma: integrative genomics analysis outlines mixed miRNA-TF circuits and pathway-derived networks modulated in t(4;14) patients
Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia
Rescue of Hippo coactivator YAP1 triggers DNA damage–induced apoptosis in hematological cancers
Targeting Mcl-1 for multiple myeloma (MM) therapy: Drug-induced generation of Mcl-1 fragment Mcl-1128–350 triggers MM cell death via c-Jun upregulation
Targeting Mcl-1 for Multiple Myeloma (MM) Therapy: Drug-Induced Generation of Mcl-1 Fragment Mcl-1128–350 Triggers MM Cell Death Via c- Jun Upregulation