Area of research
Molecular Biology · Rheumatology
Research interest
Research interests include Systemic Lupus Erythematosus Research, Cellular transport and secretion, Galectins and Cancer Biology, and Glycosylation and Glycoproteins Research.
Galectin-8 regulates primary cilium in hypothalamic neurons through an L-type calcium channel/Aurora kinase A/HDAC6 pathway impacting body energy balance
Anti-P antibodies that impair memory perturb hippocampal glutamatergic receptor trafficking, synapse structure and microglia.
Galectin-8 drives ERK-dependent mitochondrial fragmentation, perinuclear relocation and mitophagy, with metabolic adaptations for cell proliferation.
Endogenous Galectin-8 protects against Th17 infiltration and fibrosis following acute kidney injury.
HERPUD1 mediates palmitic acid-induced UPR sustaining TNBC aggressiveness and is destabilized by CK2 pharmacological inhibition.
Curcumin Improves Hippocampal Cell Bioenergetics, Redox and Inflammatory Markers, and Synaptic Proteins, Regulating Mitochondrial Calcium Homeostasis.
Galectins in epithelial-mesenchymal transition: roles and mechanisms contributing to tissue repair, fibrosis and cancer metastasis.
The Global Kidney Patient Trials Network and the CAPTIVATE Platform Clinical Trial Design
Galectin-8 counteracts folic acid-induced acute kidney injury and prevents its transition to fibrosis.
Progress in the mechanism of neuronal surface P antigen modulating hippocampal function and implications for autoimmune brain disease.
Sonic hedgehog is basolaterally sorted from the TGN and transcytosed to the apical domain involving Dispatched-1 at Rab11-ARE.
Phosphatidic acid-PKA signaling regulates p38 and ERK1/2 functions in ligand-independent EGFR endocytosis.
D-Propranolol Impairs EGFR Trafficking and Destabilizes Mutant p53 Counteracting AKT Signaling and Tumor Malignancy.
Sonic hedgehog is basolaterally sorted from the TGN and transcytosed to the apical domain involving Dispatched-1 at Rab11-ARE
Galectins in the brain: advances in neuroinflammation, neuroprotection and therapeutic opportunities.
Neuronal surface P antigen (NSPA) modulates postsynaptic NMDAR stability through ubiquitination of tyrosine phosphatase PTPMEG.
Galectin-8 mediates fibrogenesis induced by cyclosporine in human gingival fibroblasts.
Letter to the Editor in response to the article "A review and meta-analysis of anti-ribosomal P autoantibodies in systemic lupus erythematosus." by Choi M, FitzPatrick R, Buhler K, Mahler M, Fritzler M, Autoimmun Rev. 2020 March;19(3):102463.
Fact or Fiction, It Is Time for a Verdict on Vasculogenic Mimicry?
KDEL receptor regulates secretion by lysosome relocation- and autophagy-dependent modulation of lipid-droplet turnover.
GALECTIN-8 Is a Neuroprotective Factor in the Brain that Can Be Neutralized by Human Autoantibodies.
Galectin-8 induces endothelial hyperpermeability through the eNOS pathway involving S-nitrosylation-mediated adherens junction disassembly.
Predictors of damage accrual in systemic lupus erythematosus: a longitudinal observational study with focus on neuropsychological factors and anti-neuronal antibodies.