Area of research
Molecular Biology · Public Health, Environmental and Occupational Health
Research interest
Research interests include DNA Repair Mechanisms, CRISPR and Genetic Engineering, Genomics and Chromatin Dynamics, and Reproductive Biology and Fertility.
Aggressive Serous Carcinomas of the Female Reproductive Tract: Cancer-Prone Cell States and Genetic Drivers
Pre-ciliated tubal epithelial cells are prone to initiation of high-grade serous ovarian carcinoma
Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome
Prime editing in mice reveals the essentiality of a single base in driving tissue-specific gene expression
SKP1 drives the prophase I to metaphase I transition during male meiosis
Testis formation in XX individuals resulting from novel pathogenic variants in Wilms’ tumor 1 ( <i>WT1</i> ) gene
Oocyte Elimination Through DNA Damage Signaling from CHK1/CHK2 to p53 and p63
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
The DNA Damage Checkpoint Eliminates Mouse Oocytes with Chromosome Synapsis Failure
Mechanism and Regulation of Rapid Telomere Prophase Movements in Mouse Meiotic Chromosomes
MEI4: a central player in the regulation of meiotic DNA double strand break formation in the mouse
<scp>MCM</scp>9 deficiency delays primordial germ cell proliferation independent of the <scp>ATM</scp> pathway
A Mouse Geneticist’s Practical Guide to CRISPR Applications
Reversal of Female Infertility by <i>Chk2</i> Ablation Reveals the Oocyte DNA Damage Checkpoint Pathway
Antagonistic roles of ubiquitin ligase HEI10 and SUMO ligase RNF212 regulate meiotic recombination
miR-34 Cooperates with p53 in Suppression of Prostate Cancer by Joint Regulation of Stem Cell Compartment
Applying “Gold Standards” to In-Vitro-Derived Germ Cells
STAG3 is a strong candidate gene for male infertility
An Ancient Transcription Factor Initiates the Burst of piRNA Production during Early Meiosis in Mouse Testes
Female Mice Lacking Estrogen Receptor-Alpha in Osteoblasts Have Compromised Bone Mass and Strength
The MCM8-MCM9 Complex Promotes RAD51 Recruitment at DNA Damage Sites To Facilitate Homologous Recombination
MCM4 mutation causes adrenal failure, short stature, and natural killer cell deficiency in humans
Tissue-Specific Functional Networks for Prioritizing Phenotype and Disease Genes
Meiotic cohesin complexes are essential for the formation of the axial element in mice
MARF1 Regulates Essential Oogenic Processes in Mice
Genetics of Meiosis and Recombination in Mice
Phosphorylation of Chromosome Core Components May Serve as Axis Marks for the Status of Chromosomal Events during Mammalian Meiosis
Interallelic and Intergenic Incompatibilities of the Prdm9 (Hst1) Gene in Mouse Hybrid Sterility
Genetics of Meiotic Drive and Infertility in Mouse T Haplotypes
Mouse "t" Complex Meeting: to be held September 29-October 2, 1996, Jackson Laboratory, Bar Harbor, Maine
The Mouse: Acquiring and Disseminating Biological Data
Presidential Young Investigator Award
Presidential Young Investigator Award