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Frank Bruchertseifer

European Commission · BE
Area of research
Radiology, Nuclear Medicine and Imaging · Pulmonary and Respiratory Medicine
Research interest
Research interests include Radiopharmaceutical Chemistry and Applications, Prostate Cancer Treatment and Research, Medical Imaging Techniques and Applications, and Monoclonal and Polyclonal Antibodies Research.
h-index
54
citations
10,587
works
363
NIH funding
primary concept
Medicine
email

Recent publications

Actinium-225-PSMA radioligand therapy of metastatic castration-resistant prostate cancer (WARMTH Act): a multicentre, retrospective study
The Lancet Oncology 2024cited by 171position: middledoi
Deescalated<sup>225</sup>Ac-PSMA-617 Versus<sup>177</sup>Lu/<sup>225</sup>Ac-PSMA-617 Cocktail Therapy: A Single-Center Retrospective Analysis of 233 Patients
Journal of Nuclear Medicine 2024cited by 28position: middledoi
Production of innovative radionuclides for medical applications at the CERN-MEDICIS facility
Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms 2023cited by 8position: middledoi
Data from Preclinical Evaluation of &lt;sup&gt;225&lt;/sup&gt;Ac-Labeled Single-Domain Antibody for the Treatment of HER2&lt;sup&gt;pos&lt;/sup&gt; Cancer
2023cited by 0position: contributordoi
Supplementary Data from Preclinical Evaluation of &lt;sup&gt;225&lt;/sup&gt;Ac-Labeled Single-Domain Antibody for the Treatment of HER2&lt;sup&gt;pos&lt;/sup&gt; Cancer
2023cited by 0position: contributordoi
Supplementary Data from Preclinical Evaluation of &lt;sup&gt;225&lt;/sup&gt;Ac-Labeled Single-Domain Antibody for the Treatment of HER2&lt;sup&gt;pos&lt;/sup&gt; Cancer
2023cited by 0position: contributordoi
Data from Preclinical Evaluation of &lt;sup&gt;225&lt;/sup&gt;Ac-Labeled Single-Domain Antibody for the Treatment of HER2&lt;sup&gt;pos&lt;/sup&gt; Cancer
2023cited by 0position: contributordoi
Preclinical Evaluation of 225Ac-Labeled Single-Domain Antibody for the Treatment of HER2pos Cancer.
2022cited by 19position: contributordoi
Production and Supply of α-Particle–Emitting Radionuclides for Targeted α-Therapy
Journal of Nuclear Medicine 2021cited by 121position: middledoi
Dosing 225Ac-DOTATOC in patients with somatostatin-receptor-positive solid tumors: 5-year follow-up of hematological and renal toxicity
European Journal of Nuclear Medicine and Molecular Imaging 2021cited by 81position: middledoi
CERN-MEDICIS: A Review Since Commissioning in 2017
Frontiers in Medicine 2021cited by 36position: middledoi
Radiochemical separation of 224Ra from 232U and 228Th sources for 224Ra/212Pb/212Bi generator
Applied Radiation and Isotopes 2021cited by 20position: contributordoi
Diverse metabolic response of cancer cells treated with a 213Bi-anti-EGFR-immunoconjugate
Scientific Reports 2021cited by 8position: middledoi
Activity and Adverse Events of Actinium-225-PSMA-617 in Advanced Metastatic Castration-resistant Prostate Cancer After Failure of Lutetium-177-PSMA
European Urology 2020cited by 263position: middledoi
Therapeutic Efficacy of <sup>213</sup>Bi-labeled sdAbs in a Preclinical Model of Ovarian Cancer
Molecular Pharmaceutics 2020cited by 58position: middledoi
First patient exceeding 5-year complete remission after 225Ac-PSMA-TAT
European Journal of Nuclear Medicine and Molecular Imaging 2020cited by 25position: middledoi
Patients Resistant Against PSMA-Targeting α-Radiation Therapy Often Harbor Mutations in DNA Damage-Repair–Associated Genes
Journal of Nuclear Medicine 2019cited by 83position: middledoi
DNA damage in human whole blood caused by radiopharmaceuticals evaluated by the comet assay
Mutagenesis 2019cited by 22position: middledoi
Assessment of 213Bi-anti-EGFR MAb treatment efficacy in malignant cancer cells with [1-13C]pyruvate and [18F]FDG
Scientific Reports 2019cited by 8position: middledoi
Targeted α-Therapy of Metastatic Castration-Resistant Prostate Cancer with <sup>225</sup>Ac-PSMA-617: Swimmer-Plot Analysis Suggests Efficacy Regarding Duration of Tumor Control
Journal of Nuclear Medicine 2018cited by 420position: middledoi
An Overview of Targeted Alpha Therapy with <sup>225</sup>Actinium and <sup>213</sup>Bismuth
Current Radiopharmaceuticals 2018cited by 356position: lastdoi
Initial clinical experience performing sialendoscopy for salivary gland protection in patients undergoing 225Ac-PSMA-617 RLT
European Journal of Nuclear Medicine and Molecular Imaging 2018cited by 94position: middledoi
Targeted α-Therapy of Metastatic Castration-Resistant Prostate Cancer with <sup>225</sup>Ac-PSMA-617: Dosimetry Estimate and Empiric Dose Finding
Journal of Nuclear Medicine 2017cited by 492position: middledoi
Targeted alpha therapy of mCRPC: Dosimetry estimate of 213Bismuth-PSMA-617
European Journal of Nuclear Medicine and Molecular Imaging 2017cited by 141position: middledoi
<sup>225</sup>Ac-PSMA-617 for PSMA-Targeted α-Radiation Therapy of Metastatic Castration-Resistant Prostate Cancer
Journal of Nuclear Medicine 2016cited by 1,075position: middledoi
213Bi-DOTATOC receptor-targeted alpha-radionuclide therapy induces remission in neuroendocrine tumours refractory to beta radiation: a first-in-human experience
European Journal of Nuclear Medicine and Molecular Imaging 2014cited by 395position: middledoi
DNA Double Strand Breaks as Predictor of Efficacy of the Alpha-Particle Emitter Ac-225 and the Electron Emitter Lu-177 for Somatostatin Receptor Targeted Radiotherapy
PLoS ONE 2014cited by 137position: middledoi
213Bi-anti-EGFR radioimmunoconjugates and X-ray irradiation trigger different cell death pathways in squamous cell carcinoma cells
Nuclear Medicine and Biology 2013cited by 8position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Clemens Kratochwil · German Center for Lung Research13 papers (2014–2024)Aliyah Morgenstern · Université Sorbonne Nouvelle13 papers (2014–2024)Frederik L. Giesel · Düsseldorf University Hospital10 papers (2014–2024)Uwe Haberkorn · Heidelberg University10 papers (2014–2024)Hendrik Rathke · Kantonsspital Graubünden8 papers (2017–2024) · 6 papers (2014–2021) · 6 papers (2021–2023) · 6 papers (2013–2021)Marek Pruszynski · Duke University5 papers (2022–2023)Peter Covens · Vrije Universiteit Brussel5 papers (2022–2023)Tony Lahoutte · Vrije Universiteit Brussel5 papers (2022–2023)Brian W. Miller · Pacific Northwest National Laboratory5 papers (2022–2023)Matthijs B. Sevenois · Vrije Universiteit Brussel5 papers (2022–2023)Vicky Caveliers · Vrije Universiteit Brussel5 papers (2022–2023)Magdalena Rodak · Institute of Nuclear Chemistry and Technology5 papers (2022–2023)Matthias D'Huyvetter · Vrije Universiteit Brussel5 papers (2022–2023)Alfred Morgenstern · Joint Research Centre5 papers (2022–2023)Yana Dekempeneer · 5 papers (2022–2023)Maria Wojewódzka · Instytut Chemii i Techniki Jądrowej5 papers (2022–2023)Christof Seidl · Technical University of Munich4 papers (2013–2021)