Area of research
Immunology · Oncology
Research interest
Research interests include Immune cells in cancer, Cancer Immunotherapy and Biomarkers, Immunotherapy and Immune Responses, and Immune Cell Function and Interaction.
CD300ld blockade overcomes PMN-MDSC-mediated vaccine resistance in advanced tumors.
Dual function of DOT1L suppresses tumor cell-intrinsic immunogenicity in hepatocellular carcinoma.
Tumor-derived branched-chain α-keto acids activate Notch signaling in tumor-associated macrophages to limit immunity.
Amphotericin B promotes respiratory viral entry by enhancing late endosomal maturation and fusion via glucocerebrosidase-mediated ceramide remodeling.
CD300ld on pathologically activated neutrophils promotes tumor immune suppression by binding phosphatidylserine on CD8<sup>+</sup> T cells.
Intratumoral heterogeneity and drug resistance in cancer
Neoantigen enriched biomimetic nanovaccine for personalized cancer immunotherapy
Neoantigen enriched biomimetic nanovaccine for personalized cancer immunotherapy.
True-Triaxial Investigation on Failure Characteristics of Rock Mass with Varying Discontinuous Joint Occurrence: Experimental and Numerical Approaches
MYO1F in neutrophils is required for the response to immune checkpoint blockade therapy.
Circulating tumor cells shielded with extracellular vesicle-derived CD45 evade T cell attack to enable metastasis
Annexin A2 promotes proliferative vitreoretinopathy in response to a macrophage inflammatory signal in mice
Targeting PMN-MDSCs via CD300ld receptor for cancer immunotherapy.
Cell surface protein-protein interaction profiling for biological network analysis and novel target discovery.
CD300ld on neutrophils is required for tumour-driven immune suppression
CD300ld on neutrophils is required for tumour-driven immune suppression.
A20 promotes colorectal cancer immune evasion by upregulating STC1 expression to block “eat-me” signal
Loss of ESRP2 Activates TAK1‐MAPK Signaling through the Fetal RNA‐Splicing Program to Promote Hepatocellular Carcinoma Progression
Protein disulfide-isomerase A4 confers glioblastoma angiogenesis promotion capacity and resistance to anti-angiogenic therapy
Epigenetic activation of the TUSC3 gene as a potential therapy for XMEN disease.
Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2.
Intratumoral administration of STING-activating nanovaccine enhances T cell immunotherapy
Intratumoral administration of STING-activating nanovaccine enhances T cell immunotherapy.
M2‐like macrophage‐derived exosomes facilitate metastasis in non‐small‐cell lung cancer by delivering integrin αVβ3
Comprehensive analysis of the prognostic implications and functional exploration of PAK gene family in human cancer
Efficient expansion of mouse hematopoietic stem cells ex vivo by membrane anchored Angptl2.
Author Correction: Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2.
Prolonged activation of innate immune pathways by a polyvalent STING agonist.
Comprehensive single-cell sequencing reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of nasopharyngeal carcinoma
Intercellular transfer of exosomal wild type EGFR triggers osimertinib resistance in non-small cell lung cancer