Area of research
Genetics · Oncology
Research interest
Research interests include Virus-based gene therapy research, CAR-T cell therapy research, Cancer Research and Treatments, and Virology and Viral Diseases.
Biomarker screen for efficacy of oncolytic virotherapy in patient-derived pancreatic cancer cultures
A vector-encoded bispecific killer engager to harness virus-activated NK cells as anti-tumor effectors
Oncolytic Measles Virus Encoding MicroRNA for Targeted RNA Interference
Virotherapy combined with anti-PD-1 transiently reshapes the tumor immune environment and induces anti-tumor immunity in a preclinical PDAC model
Advances in oncolytic virotherapy
Safety study supports clinical development of immunotherapeutic oncolytic measles vaccine
Oncolytic viruses encoding bispecific T cell engagers: a blueprint for emerging immunovirotherapies
Measles Virus as an Oncolytic Immunotherapy
Phase 2 Trial of Oncolytic H-1 Parvovirus Therapy Shows Safety and Signs of Immune System Activation in Patients With Metastatic Pancreatic Ductal Adenocarcinoma
Virotherapy in Germany—Recent Activities in Virus Engineering, Preclinical Development, and Clinical Studies
MicroRNA-sensitive oncolytic measles virus for chemovirotherapy of pancreatic cancer
Oncolytic measles vaccines encoding PD-1 and PD-L1 checkpoint blocking antibodies to increase tumor-specific T cell memory
Mechanisms of measles virus oncolytic immunotherapy
Measles Vaccines Designed for Enhanced CD8+ T Cell Activation
Sequencing of serially passaged measles virus affirms its genomic stability and reveals a nonrandom distribution of consensus mutations
Re: “Oncolytic Measles Virus Encoding Interleukin-12 Mediated Antitumor Activity and Immunologic Control of Colon Cancer <i>In Vivo</i> and <i>Ex Vivo</i> ” by Wang et al.
Tumor-Specific Delivery of Immune Checkpoint Inhibitors by Engineered AAV Vectors
Immunological Effects and Viral Gene Expression Determine the Efficacy of Oncolytic Measles Vaccines Encoding IL-12 or IL-15 Agonists
Introduction to Oncolytic Virotherapy
Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
Mathematical Modeling of Oncolytic Virotherapy
Immunomodulation in Oncolytic Measles Virotherapy
Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
Enhanced Control of Oncolytic Measles Virus Using MicroRNA Target Sites
Oncolytic measles virus encoding interleukin-12 mediates potent antitumor effects through T cell activation
A non-controlled, single arm, open label, phase II study of intravenous and intratumoral administration of ParvOryx in patients with metastatic, inoperable pancreatic cancer: ParvOryx02 protocol
Fighting Cancer with Mathematics and Viruses
Virotherapy Research in Germany: From Engineering to Translation
A Tupaia paramyxovirus vector system for targeting and transgene expression