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Torsten Tonn

Goethe University Frankfurt · DE
Area of research
Immunology · Oncology
Research interest
Research interests include CAR-T cell therapy research, Immune Cell Function and Interaction, Mesenchymal stem cell research, and SARS-CoV-2 and COVID-19 Research.
h-index
57
citations
16,539
works
283
NIH funding
primary concept
email

Recent publications

CAR-NK cell therapy combined with checkpoint inhibition induces an NKT cell response in glioblastoma
British Journal of Cancer 2025cited by 17position: middledoi
ErbB2/HER2-targeted CAR-NK cells eliminate breast cancer cells in an organoid model that recapitulates tumor progression
Molecular Therapy 2025cited by 10position: middledoi
Clonal hematopoiesis landscape in frequent blood donors
Blood 2025cited by 8position: middledoi
Blood-based detection of MMP11 as a marker of prostate cancer progression regulated by the ALDH1A1-TGF-β1 signaling mechanism
Journal of Experimental & Clinical Cancer Research 2025cited by 4position: middledoi
CAR-mediated targeting of NK cells overcomes tumor immune escape caused by ICAM-1 downregulation
Journal for ImmunoTherapy of Cancer 2024cited by 35position: lastdoi
Blood-based detection of MMP11 as a marker of prostate cancer progression regulated by the ALDH1A1-TGF-β1 signaling mechanism
bioRxiv (Cold Spring Harbor Laboratory) 2024cited by 1position: middledoi
Intracranial injection of natural killer cells engineered with a HER2-targeted chimeric antigen receptor in patients with recurrent glioblastoma
Neuro-Oncology 2023cited by 117position: middledoi
Impedimetric Nanobiosensor for the Detection of SARS-CoV-2 Antigens and Antibodies
ACS Sensors 2023cited by 36position: middledoi
Ecological and clinical evidence of the establishment of West Nile virus in a large urban area in Europe, Berlin, Germany, 2021 to 2022
Eurosurveillance 2023cited by 20position: middledoi
ErbB2 (HER2)-CAR-NK-92 cells for enhanced immunotherapy of metastatic fusion-driven alveolar rhabdomyosarcoma
Frontiers in Immunology 2023cited by 16position: middledoi
Multivalent adaptor proteins specifically target NK cells carrying a universal chimeric antigen receptor to ErbB2 (HER2)-expressing cancers
Cancer Immunology Immunotherapy 2023cited by 8position: middledoi
Palbociclib impairs the proliferative capacity of activated T cells while retaining their cytotoxic efficacy
Frontiers in Pharmacology 2023cited by 8position: middledoi
Serum immune checkpoint profiling identifies soluble CD40 as a biomarker for pancreatic cancer
npj Precision Oncology 2023cited by 7position: middledoi
9-Month observational Dia-Vacc study of vaccine type influence on SARS-CoV-2 immunity in dialysis and kidney transplant patients
Vaccine 2023cited by 6position: middledoi
AAV-mediated gene transfer of a checkpoint inhibitor in combination with HER2-targeted CAR-NK cells as experimental therapy for glioblastoma
OncoImmunology 2022cited by 52position: middledoi
NKG2C+ NK Cells for Immunotherapy of Glioblastoma Multiforme
International Journal of Molecular Sciences 2022cited by 25position: middledoi
One-year follow-up of the CAPSID randomized trial for high-dose convalescent plasma in severe COVID-19 patients
Journal of Clinical Investigation 2022cited by 22position: middledoi
Perturbations of mesenchymal stromal cells after allogeneic hematopoietic cell transplantation predispose for bone marrow graft-versus-host-disease
Frontiers in Immunology 2022cited by 2position: middledoi
Humoral and cellular immunity to SARS-CoV-2 vaccination in renal transplant versus dialysis patients: A prospective, multicenter observational study using mRNA-1273 or BNT162b2 mRNA vaccine
The Lancet Regional Health - Europe 2021cited by 309position: middledoi
SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care
Nature Communications 2021cited by 169position: middledoi
Potential benefit of convalescent plasma transfusions in immunocompromised patients with COVID-19
The Lancet Microbe 2021cited by 50position: middledoi
Donors for SARS-CoV-2 Convalescent Plasma for a Controlled Clinical Trial: Donor Characteristics, Content and Time Course of SARS-CoV-2 Neutralizing Antibodies
Transfusion Medicine and Hemotherapy 2021cited by 25position: middledoi
“UniCAR”-modified off-the-shelf NK-92 cells for targeting of GD2-expressing tumour cells
Scientific Reports 2020cited by 82position: middledoi
Stability and neutralising capacity of SARS-CoV-2-specific antibodies in convalescent plasma
The Lancet Microbe 2020cited by 32position: firstdoi
P06.12 Combination therapy of CAR-NK-cells and anti-PD-1 antibody results in high efficacy against advanced-stage glioblastoma in a syngeneic mouse model and induces protective anti-tumor immunity <i>in vivo</i>
2020cited by 3position: middledoi
P06.13 A novel local treatment approach? Targeted immunotherapy of glioblastoma via AAV-mediated gene transfer of checkpoint inhibitors through locally administered HER2-AAVs in combination with CAR-NK cells
2020cited by 1position: middledoi
CAR-Engineered NK Cells for the Treatment of Glioblastoma: Turning Innate Effectors Into Precision Tools for Cancer Immunotherapy
Frontiers in Immunology 2019cited by 203position: middledoi
Low level of exosomal long non-coding RNA <i>HOTTIP</i> is a prognostic biomarker in colorectal cancer
RNA Biology 2019cited by 103position: middledoi
Expression of Glypican 3 Is an Independent Prognostic Biomarker in Primary Gastro-Esophageal Adenocarcinoma and Corresponding Serum Exosomes
Journal of Clinical Medicine 2019cited by 18position: middledoi
P12.04 Synergistic effects of combination therapy of CAR-NK cells and anti-PD-1 antibody result in high efficacy against advanced stage orthotopic glioblastoma grafts in a syngeneic mouse model and induce protective anti-tumor immunity in vivo
Neuro-Oncology 2019cited by 3position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Winfried S. Wels · Goethe University Frankfurt15 papers (2014–2025)Congcong Zhang · Miltenyi Biotec (Germany)9 papers (2014–2025)Marc Schmitz · German Cancer Research Center8 papers (2015–2023)Michael Bachmann · Heidelberg University8 papers (2015–2024)Erhard Seifried · German Red Cross7 papers (2013–2021)Martin Bornhäuser · German Cancer Research Center7 papers (2014–2022)Marcus Odendahl · University Hospital Frankfurt6 papers (2014–2018)F Straßheimer · Goethe University Frankfurt6 papers (2019–2025)Anja Feldmann · German Cancer Research Center5 papers (2020–2024)Hans Klingemann · Tufts University5 papers (2013–2024)Rebekka Wehner · German Cancer Research Center5 papers (2015–2023)Antje Tunger · German Cancer Research Center4 papers (2016–2023)Victor M. Corman · Humboldt-Universität zu Berlin4 papers (2020–2023)Halvard Bönig · Goethe-Institute United Kingdom4 papers (2014–2023)Tijna Alekseeva · Johannes Gutenberg University Mainz4 papers (2020–2025)Christian Drosten · University of Edinburgh4 papers (2020–2023)Michael C. Burger · Goethe University Frankfurt4 papers (2015–2025)Evelyn Ullrich · Goethe University Frankfurt4 papers (2013–2023)Maja Strecker · Goethe University Frankfurt4 papers (2019–2022)Christoph Kahlert · Heidelberg University3 papers (2019–2023)