Area of research
Infectious Diseases · Hepatology
Research interest
Research interests include Hepatitis C virus research, Hepatitis B Virus Studies, HIV/AIDS drug development and treatment, and SARS-CoV-2 and COVID-19 Research.
The Discovery and Preclinical Profile of ALG-000184, a Prodrug of the Potent Hepatitis B Virus Capsid Assembly Modulator ALG-001075
Deep mutational scanning identifies SARS-CoV-2 Nucleocapsid escape mutations of currently available rapid antigen tests
The Mechanism of Action of Hepatitis B Virus Capsid Assembly Modulators Can Be Predicted from Binding to Early Assembly Intermediates
Baicalein and Baicalin Inhibit SARS-CoV-2 RNA-Dependent-RNA Polymerase
Multidisciplinary assessment of the Abbott BinaxNOW SARS-CoV-2 point-of-care antigen test in the context of emerging viral variants and self-administration
Comparison of anti-SARS-CoV-2 activity and intracellular metabolism of remdesivir and its parent nucleoside
Single-Amplicon Multiplex Real-Time Reverse Transcription-PCR with Tiled Probes To Detect SARS-CoV-2 <i>spike</i> Mutations Associated with Variants of Concern
Encephalopathy and Encephalitis Associated with Cerebrospinal Fluid Cytokine Alterations and Coronavirus Disease, Atlanta, Georgia, USA, 2020
Repurposing Nucleoside Analogs for Human Coronaviruses
Antibody Profiles According to Mild or Severe SARS-CoV-2 Infection, Atlanta, Georgia, USA, 2020
Potent in vitro activity of β-D-4ʹ-chloromethyl-2ʹ-deoxy-2ʹ-fluorocytidine against Nipah virus
Novel Hepatitis B Virus Capsid Assembly Modulator Induces Potent Antiviral Responses <i>In Vitro</i> and in Humanized Mice
Nucleoside Analogs with Selective Antiviral Activity against Dengue Fever and Japanese Encephalitis Viruses
Discovery of a Series of 2′-α-Fluoro,2′-β-bromo-ribonucleosides and Their Phosphoramidate Prodrugs as Potent Pan-Genotypic Inhibitors of Hepatitis C Virus
Towards <scp>HBV</scp> curative therapies
Zika in the Americas, year 2: What have we learned? What gaps remain? A report from the Global Virus Network
Synthesis of sulfamoylbenzamide derivatives as HBV capsid assembly effector
2′-Chloro,2′-fluoro Ribonucleotide Prodrugs with Potent Pan-genotypic Activity against Hepatitis C Virus Replication in Culture
Toward Elimination of Hepatitis B Virus Using Novel Drugs, Approaches, and Combined Modalities
β-<scp>d</scp>-2′-<i>C</i>-Methyl-2,6-diaminopurine Ribonucleoside Phosphoramidates are Potent and Selective Inhibitors of Hepatitis C Virus (HCV) and Are Bioconverted Intracellularly to Bioactive 2,6-Diaminopurine and Guanosine 5′-Triphosphate Forms
Suppression of hepatitis B virus DNA accumulation in chronically infected cells using a bacterial CRISPR/Cas RNA-guided DNA endonuclease
Approaches to hepatitis C treatment and cure using NS5A inhibitors
Cellular Pharmacology and Potency of HIV-1 Nucleoside Analogs in Primary Human Macrophages