Area of research
Immunology · Molecular Biology
Research interest
Research interests include T-cell and B-cell Immunology, CRISPR and Genetic Engineering, Advanced biosensing and bioanalysis techniques, and Liver physiology and pathology.
Image-guided injectable niche for hepatocyte transplantation
Priming agents transiently reduce the clearance of cell-free DNA to improve liquid biopsies
Autonomous circadian rhythms in the human hepatocyte regulate hepatic drug metabolism and inflammatory responses
Inhalable point-of-care urinary diagnostic platform
Targeting and monitoring ovarian cancer invasion with an RNAi and peptide delivery system
CRISPR-Cas-amplified urinary biomarkers for multiplexed and portable cancer diagnostics
CRISPR-Cas-mediated Multianalyte Synthetic Urine Biomarker Test for Portable Diagnostics
A single-cell liver atlas of Plasmodium vivax infection
Conditional Antimicrobial Peptide Therapeutics
A vascularized model of the human liver mimics regenerative responses
Microenvironment-triggered multimodal precision diagnostics
Synthetic Circuit-Driven Expression of Heterologous Enzymes for Disease Detection
Gene signatures and host-parasite interactions revealed by dual single-cell profiling of <i>Plasmodium vivax</i> liver infection
Urinary detection of lung cancer in mice via noninvasive pulmonary protease profiling
Controlled Apoptosis of Stromal Cells to Engineer Human Microlivers
Tissue Engineering: Controlled Apoptosis of Stromal Cells to Engineer Human Microlivers (Adv. Funct. Mater. 48/2020)
Hepatic tissue engineering
Synthetic and living micropropellers for convection-enhanced nanoparticle transport
Non-viral delivery of CRISPR/Cas9 complex using CRISPR-GPS nanocomplexes
Improving Drug Discovery by Nucleic Acid Delivery in Engineered Human Microlivers
In Vitro Culture, Drug Sensitivity, and Transcriptome of Plasmodium Vivax Hypnozoites
Protease activity sensors noninvasively classify bacterial infections and antibiotic responses
In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease
Development of Light‐Activated CRISPR Using Guide RNAs with Photocleavable Protectors
Development of Light‐Activated CRISPR Using Guide RNAs with Photocleavable Protectors
Extracellular matrix microarrays to study inductive signaling for endoderm specification
Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens
Pluripotent stem cell-derived hepatocyte-like cells