Area of research
Oncology · Physiology
Research interest
Research interests include Cancer-related Molecular Pathways, Telomeres, Telomerase, and Senescence, Epigenetics and DNA Methylation, and Pancreatic and Hepatic Oncology Research.
Regulation of cell function and identity by cellular senescence
Removal of senescent cells reduces the viral load and attenuates pulmonary and systemic inflammation in SARS-CoV-2-infected, aged hamsters
Eliminating Senescent Cells Can Promote Pulmonary Hypertension Development and Progression
Expression of the Calcium-Binding Protein CALB1 Is Induced and Controls Intracellular Ca2+ Levels in Senescent Cells
<scp>NF‐κB</scp>‐dependent secretome of senescent cells can trigger neuroendocrine transdifferentiation of breast cancer cells
Transformed cells after senescence give rise to more severe tumor phenotypes than transformed non-senescent cells
Calcium channel ITPR2 and mitochondria–ER contacts promote cellular senescence and aging
PLA2R1 promotes DNA damage and inhibits spontaneous tumor formation during aging
Oncogene-Induced Senescence Limits the Progression of Pancreatic Neoplasia through Production of Activin A
The antioxidant N-acetylcysteine protects from lung emphysema but induces lung adenocarcinoma in mice
Transcriptional repression of DNA repair genes is a hallmark and a cause of cellular senescence
The <scp>SCN</scp> 9A channel and plasma membrane depolarization promote cellular senescence through Rb pathway