Richard L. Roudebush VA Medical Center · US
Area of research
Hepatology · Epidemiology
Research interest
Research interests include Liver Disease Diagnosis and Treatment, Liver Diseases and Immunity, Liver physiology and pathology, and Pediatric Hepatobiliary Diseases and Treatments.
Cellular Interactions and Crosstalk Facilitating Biliary Fibrosis in Cholestasis.
Fibroblast Growth Factor 19 in Alcohol-Associated Liver Disease: Bile Acids and Dysbiosis and Inflammation, Oh My!
Sex-Dependent Differences in Cholestasis
p16 INK4A drives nonalcoholic fatty liver disease phenotypes in high fat diet fed mice through biliary E2F1/FOXO1/IGF-1 signaling.
Loss of apical sodium bile acid transporter alters bile acid circulation and reduces biliary damage in cholangitis.
Prolonged administration of a secretin receptor antagonist inhibits biliary senescence and liver fibrosis in Mdr2 -/- mice.
Development of Scaffold-Free Three-Dimensional Cholangiocyte Organoids to Study the Progression of Primary Sclerosing Cholangitis
Role of ductular reaction and ductular–canalicular junctions in identifying severe primary biliary cholangitis
Melatonin receptor 1A, but not 1B, knockout decreases biliary damage and liver fibrosis during cholestatic liver injury.
Mast cells in liver disease progression: An update on current studies and implications.
Three-Dimensional Organoids as a Model to Study Nonalcoholic Fatty Liver Disease.
Mast cells selectively target large cholangiocytes during biliary injury via H2HR-mediated cAMP/pERK1/2 signaling.
FGF1 Signaling Modulates Biliary Injury and Liver Fibrosis in the Mdr2<sup>-/-</sup> Mouse Model of Primary Sclerosing Cholangitis.
HNRNPM Regulates HCC Tumorigenesis and Cancer Stemness: Identification of a Novel Therapeutic Target?
Development of Scaffold-free 3D Cholangiocyte Organoids to Study the Progression of Primary Sclerosing Cholangitis
Organoids and Spheroids as Models for Studying Cholestatic Liver Injury and Cholangiocarcinoma.
Mast Cells Regulate Ductular Reaction and Intestinal Inflammation in Cholestasis Through Farnesoid X Receptor Signaling.
Mast Cells Promote Nonalcoholic Fatty Liver Disease Phenotypes and Microvesicular Steatosis in Mice Fed a Western Diet.
Impact of Aging on Liver Cells and Liver Disease: Focus on the Biliary and Vascular Compartments.
Biliary Epithelial Senescence in Liver Disease: There Will Be SASP.
Inhibition of Secretin/Secretin Receptor Axis Ameliorates NAFLD Phenotypes.
Feedback Signaling between Cholangiopathies, Ductular Reaction, and Non-Alcoholic Fatty Liver Disease.
Cyclic AMP Signaling in Biliary Proliferation: A Possible Target for Cholangiocarcinoma Treatment?
Current Advances in Basic and Translational Research of Cholangiocarcinoma.
Secretin/secretin receptor signaling mediates biliary damage and liver fibrosis in early‐stage primary biliary cholangitis
Regulation of the Extrinsic Apoptotic Pathway by MicroRNA-21 in Alcoholic Liver Injury