Lucia Carbone

Complete sequencing of ape genomes

The human and non-human primate developmental GTEx projects

Yoo, D., Rhie, A., Hebbar, P. et al. Complete sequencing of ape genomes (2025). Nature . 2025 May; 641(8062):401-418

Lima AC, Okhovat M, Stendahl AM, VanCampen J, Nevonen KA, Herrera J, Li W, Harshman L, Yang R, Fedorov LM, Vigh-Conrad KA, Ahituv N, Conrad DF, Carbone L. Deletion of an evolutionarily conserved TAD boundary impacts spermatogenesis in mice (2025). Biol Reprod  Apr 13;112(4):767-779.

The complete sequence and comparative analysis of ape sex chromosomes

Structurally divergent and recurrently mutated regions of primate genomes

Complete sequencing of ape genomes

Makova KD, Pickett BD, Harris RS, Hartley GA, et al. The Complete Sequence and Comparative Analysis of Ape Sex Chromosomes (2024). Nature .  Jun;630(8016):401-411

TAD evolutionary and functional characterization reveals diversity in mammalian TAD boundary properties and function

Okhovat M, VanCampen J, Lima AC, Nevonen KA, Layman CE, Ward S, Herrera J, Stendahl AM, Yang R, Harshman L, Li W, Sheng RR, Mao Y, Fedorov L, Ndjamen B, Vigh-Conrad KA, Matthews IR, Easow SA, Chan DK, Jan TA, Eichler EE, Rugonyi S, Conrad DF, Ahituv N, Carbone L. TAD Evolutionary and functional char

Hartley G, Okhovat M, O’Neill RJ, Carbone L. (2021) Comparative analyses of gibbon centromeres reveal dynamic genus specific shifts in repeat composition. Molecular Biology and Evolution  38(9):3972-3992

Co-option of the lineage-specific <i>LAVA</i> retrotransposon in the gibbon genome

Coevolution of Genome Architecture and Social Behavior

Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia

Sequencing thousands of single-cell genomes with combinatorial indexing

Transcriptomic and epigenomic characterization of the developing bat wing

Examining Phylogenetic Relationships Among Gibbon Genera Using Whole Genome Sequence Data Using an Approximate Bayesian Computation Approach

Gibbon genome and the fast karyotype evolution of small apes

Carbone L, Harris RA, Gnerre S, Veeramah KR, Lorente-Galdos B, Huddleston J, Meyer TJ, Herrero J, Roos C, Aken B, Anaclerio F, Archidiacono N, Baker C, Barrell D, Batzer MA, Beal K, Blancher A, Bohrson CL, Brameier M, Campbell MS, Capozzi O, Casola C, and the international consortium for the sequenc

Incomplete Lineage Sorting Is Common in Extant Gibbon Genera

Carbone L, Harris RA, Mootnick AR, Milosavljevic A, Martin DI, Rocchi M, Capozzi O, Archidiacono N, Konkel MK, Walker JA, Batzer MA, de Jong PJ. (2012) Centromere remodeling in Hoolock leuconedys (Hylobatidae) by a new transposable element unique to the gibbons. Genome Biology and Evolution 4(7):648

Hartley GA, Okhovat M, Hoyt SJ, Fuller E, Pauloski N, Alexandre N, Alexandrov I, Drennan R, Dubocanin D, Gilbert DM, Mao Y, McCann C, Neph S, Ryabov F, Sasaki T, Storer JM, Svendsen D, Troy W, Wells J, Core L, Stergachis A, Carbone L, O’Neill RJ Centromeric transposable elements and epigenetic statu

Collaborative Research: Impact of a novel retrotransposon expansion on centromere function